Research on Separation Techniques for Metabolomics and Pharmacokinetics Analysis
A special issue of Separations (ISSN 2297-8739). This special issue belongs to the section "Bioanalysis/Clinical Analysis".
Deadline for manuscript submissions: 20 November 2025 | Viewed by 52
Special Issue Editor
Interests: metabolomics; pharmacokinetics; mass spectrometry; UPLC; biomarker discovery; enzyme kinetics; liver cirrhosis; drug discovery and pharmacology
Special Issue Information
Dear Colleagues,
Metabolomics and pharmacokinetics research relies on advanced separation technologies to analyze complex biological samples with high precision and sensitivity. Emerging trends in these techniques are driving significant improvements in the identification, quantification, and characterization of metabolites and drug compounds. High-performance liquid chromatography (HPLC) and gas chromatography (GC) remain widely used, but current advancements, such as ultra-high-performance liquid chromatography (UHPLC) coupled with high-resolution mass spectrometry (MS) and supercritical fluid chromatography (SFC), are improving resolution, speed, and sensitivity. Coupling these separation techniques with nuclear magnetic resonance (NMR) spectroscopy is another emerging trend, allowing for improved metabolite profiling and pharmacokinetic assessments. Additionally, microfluidic and nano-separation technologies are revolutionizing sample preparation and analysis, enabling high-throughput and miniaturized workflows. Furthermore, current uses of artificial intelligence (AI) and machine learning (ML) are further revolutionizing the separation techniques by optimizing experimental conditions and data analysis, leading to more accurate and efficient results. These advancements are crucial in drug development, biomarker discovery, and personalized medicine. As separation technologies continue to evolve, they will play a pivotal role in advancing metabolomics and pharmacokinetics research.
Dr. Mamunur Rashid
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Separations is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- metabolomics
- pharmacokinetics
- mass spectrometry
- UPLC
- supercritical fluid chromatography (SFC)
- separation technology
- biomarker discovery
- personalized medicine
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue policies can be found here.
