Sensors Integration in Organ-on-chip & Microfluidic Systems

Dear Colleagues,

Microfluidics systems offer precise fluids manipulation in micrometric controlled channels for many different applications. These miniaturised systems have demonstrated better efficiency than the conventional macroscale method for requiring fewer reagents and sample and for achieving shorter times and better yields.

The constant evolution on fabrication methods, first with 3D printing and then with bioprinting, and the progression on microfluidics and photolithography have made it possible to go a step forward to introduce in this previous technology 3D cell culturing, with the result of the organ-on-a-chip. This type of technology reproduces tissue microenvironment into a microfluidic device, including different cell types in a specific three-dimensional (3D) configuration to simulate biological systems with a concrete function. The mimicking of human systems with these platforms to predict efficiently opens up new possibilities in medicine, which is increasingly focused to personalized medicine. Moreover, drug testing or the study biological systems without requiring the use of animals is a key objective of these systems.

Sensors technology, which is able to detect events or changes in its environment at low concentrations under a complex matrix, which also permits multiparametric analyses at the same time with continuous monitoring and fast response at low cost, has brought excellent advantages in microfluidics systems. The easy integration of these systems, sharing the same fabrication technology as microfluidic platforms, makes sensors the best companion.

This Special Issue invites authors to submit reviews and original research articles related to microfluidic systems such as lab-on-a-chip (LOC), micro total analysis systems (µTAS), microelectromechanical systems (MEMS), and organ-on-a-chip (OOC) integrating sensing platforms.

Dr. Monica Mir
Dr. Lourdes Rivas Torcates
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Sensors is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• Organ-on-a-chip (OOC)
• Lab-on-a-chip (LOC) 
• Micro total analysis systems (µTAS) 
• Microelectromechanical systems (MEMS)
• Integrated (bio)sensors 
• TEER
• 3D (bio)printing 
• Microfabrication 
• Optical readout 
• Electrochemical readout