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Special Issue "Advanced Optical Biosensors"

A special issue of Sensors (ISSN 1424-8220). This special issue belongs to the section "Biosensors".

Deadline for manuscript submissions: 1 August 2019

Special Issue Editor

Guest Editor
Prof. Carlos Angulo Barrios

Instituto de Sistemas Optoelectrónicos y Microtecnología (ISOM), ETSI Telecomunicación, Universidad Politécnica de Madrid, Ciudad Universitaria s/n, 28040 Madrid, Spain
Website | E-Mail
Interests: photonics; materials science; sensors; nanotechnology

Special Issue Information

Dear Colleagues,

Optical biosensors offer appealing advantages over other types of biosensing devices. These include non-invasive, safe, and multi-dimensional (i.e., intensity, wavelength, phase, polarization) interrogation, high spatial resolution, noise-free information channels, ease of achieving 2-D array testing, the availability of well-established technologies from communication industries (e.g., lasers of almost any wavelength, detector arrays, micro-/nano-machining, waveguides and high-speed links), and the coincidence of optical frequencies with a wide range of physical properties of bio-related materials in nature. Their potential application areas include healthcare (medical diagnostics), environmental monitoring, food and agriculture control, defense, and security.
This Special Issue welcomes both reviews and original research articles in the field of optical biosensors. Topics include, but are not restricted to, surface plasmon resonance (SPR) biosensors, SPR imaging, localized SPR, evanescent wave fluorescence biosensors, bioluminescent biosensors, optical waveguide interferometric biosensors, ellipsometric biosensors, reflectometric interference spectroscopy biosensors, surface-enhanced Raman scattering biosensors, metasurface-based biosensors, and biosensing optical platforms such as lab-on-a-chip and optical fiber sensing. Fluorescent labelling, bioreceptor immobilization procedures, and the integration of synthetic receptors such as molecularly imprinted polymers into optical transducers, as well as novel concepts in both label-based and label-free schemes, and applications of this type of biosensor are also of interest. We invite and encourage your participation in this Special Issue.

Prof. Carlos Angulo Barrios
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Sensors is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • label-free optical biosensing
  • label-based optical biosensing
  • surface plasmon resonance
  • surface enhanced Raman spectroscopy
  • optical fiber sensor
  • optical waveguide
  • microelectromechanical systems
  • fluorescence biosensing
  • fluorescent labelling
  • optical interferometry
  • optical metasurfaces
  • lab on a chip
  • multiplexed detection
  • bioreceptor immobilization
  • synthetic receptors

Published Papers (1 paper)

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Open AccessArticle
Design of an Optical Probe to Monitor Vaginal Hemodynamics during Sexual Arousal
Sensors 2019, 19(9), 2129; https://doi.org/10.3390/s19092129
Received: 11 March 2019 / Revised: 2 May 2019 / Accepted: 5 May 2019 / Published: 8 May 2019
PDF Full-text (2932 KB) | HTML Full-text | XML Full-text
An optical probe was developed to measure the change of oxy-hemoglobin (OHb), deoxy- hemoglobin (RHb), and total hemoglobin (THb) along with temperature from the vaginal wall of female rats. Apomorphine (APO, 80 μg/kg) was administered to elicit sexual arousal in female Sprague Dawley [...] Read more.
An optical probe was developed to measure the change of oxy-hemoglobin (OHb), deoxy- hemoglobin (RHb), and total hemoglobin (THb) along with temperature from the vaginal wall of female rats. Apomorphine (APO, 80 μg/kg) was administered to elicit sexual arousal in female Sprague Dawley rats (SD, 180–200 g). The behavior changes caused by APO administration were checked before monitoring vaginal responses. The changes of oxy-, deoxy-, and total hemoglobin concentration and the temperature from the vaginal wall were monitored before, during, and after APO administration. Animals were under anesthesia during the measurement. After APO administration, the concentration of OHb (55 ± 29 μM/DPF), RHb (33 ± 25 μM/DPF), and THb (83 ± 59 μM/DPF) in the vaginal wall increased in a few min, while saline administration did not cause any significant change. In case of the vaginal temperature change, APO decreased the temperature slightly in the vaginal wall while saline administration did not show any temperature change in the vaginal wall. As the outcomes demonstrated, the developed probe can detect hemodynamic and temperature variation in the vaginal wall. The hemodynamic information acquired by the probe can be utilized to establish an objective and accurate standard of female sexual disorders. Full article
(This article belongs to the Special Issue Advanced Optical Biosensors)

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