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Electrochemical and Paper-Based Sensors for Point-of-Care Testing

A special issue of Sensors (ISSN 1424-8220). This special issue belongs to the section "Biomedical Sensors".

Deadline for manuscript submissions: closed (20 May 2023) | Viewed by 9015

Special Issue Editor


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Guest Editor
Future Industries Institute, University of South Australia, Campus Mawson Lakes, Mawson Lakes, SA 5095, Australia
Interests: sensor and sensing technologies; electrochemical sensors; point of care testings; solid-state sensor; field effect transistor; bioanalytical and biodiagnostics; nanomaterials and fabrication

Special Issue Information

Dear Colleagues,

While current biomarker testing is predominantly carried out within centralized pathology laboratories, recent advances in material science, nanotechnology, and biotechnology and their integration within functional, portable microsystems have collectively delivered the potential to decentralize such assays through so-called “point of care” (POC) testing. Due to its portability, cost-effectiveness, rapid response, and regulated performance, POC testing is emerging as a future trend in medical diagnostics, particularly in COVID-19 pandemic times, war zones, natural disaster/remote areas and emergency settings. With a focus on electrochemical and paper-based sensors, this Special Issue is devoted to fundamental research and translational development as well as the implementation of different types of electrochemical transducers and paper-based sensors for POC testing. The topic may include, but is not exclusively related to:

  • Electrochemical sensors, including solid-state field effect transistor: advanced material, concept, development, and validation for POC testing;
  • Paper-based sensors: advanced material, concept, development, and validation for POC testing;
  • Point of care sample processing, including microfluidics, integrated with electrochemical and paper-based sensors;
  • Clinical implementation of electrochemical and paper-based sensors for POC testing focuses on user usability/adaptability, improved patient management, and social-economic aspects.

Dr. Duy Phu Tran
Guest Editor

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Keywords

  • electrochemical sensors
  • paper-based sensors
  • microfluidics
  • nanomaterials
  • point-of-care testing
  • sample processing
  • clinical implementation

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Published Papers (1 paper)

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Review

21 pages, 4565 KiB  
Review
Lateral Flow Immunoassay Reader Technologies for Quantitative Point-of-Care Testing
by Jongwon Park
Sensors 2022, 22(19), 7398; https://doi.org/10.3390/s22197398 - 28 Sep 2022
Cited by 46 | Viewed by 8469
Abstract
Due to the recent pandemic caused by coronavirus disease 2019 (COVID-19), the lateral flow immunoassay used for its rapid antigen test is more popular than ever before. However, the history of the lateral flow immunoassay is about 60 years old, and its original [...] Read more.
Due to the recent pandemic caused by coronavirus disease 2019 (COVID-19), the lateral flow immunoassay used for its rapid antigen test is more popular than ever before. However, the history of the lateral flow immunoassay is about 60 years old, and its original purpose of use, such as a COVID-19 rapid antigen test or a pregnancy test, was the qualitative detection of a target analyte. Recently, the demand for quantitative analysis of lateral flow immunoassays is increasing in various fields. Lateral flow immunoassays for quantitative detection using various materials and sensor technologies are being introduced, and readers for analyzing them are being developed. Quantitative analysis readers are highly anticipated for their future development in line with technological advancements such as optical, magnetic field, photothermal, and electrochemical sensors and trends such as weight reduction, miniaturization, and cost reduction of systems. In addition, the sensing, processing, and communication functions of portable personal devices such as smartphones can be used as tools for the quantitative analysis of lateral flow immunoassays. As a result, lateral flow immunoassays can efficiently achieve the goal of rapid diagnosis by point-of-care testing. Readers used for the quantification of lateral flow immunoassays were classified according to the adopted sensor technology, and the research trends in each were reviewed in this paper. The development of a quantitative analysis system was often carried out in the assay aspect, so not only the readers but also the assay development cases were reviewed if necessary. In addition, systems for quantitative analysis of COVID-19, which have recently been gaining importance, were introduced as a separate section. Full article
(This article belongs to the Special Issue Electrochemical and Paper-Based Sensors for Point-of-Care Testing)
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