Biosensors in Clinical Applications

Dear Colleagues,

Healthcare relies on the capability to measure different disease markers in biofluids, not only blood and urine but also external secretions such as saliva, tears, and sweat. Since the development of the first biosensor by Clark and Lyons in 1962 for the measurement of glucose in blood, many different biosensing platforms have been developed for measuring nearly any desired analyte in these fluids. These platforms integrate a biological or biomimetic receptor, such as enzymes, antibodies, aptamers, or peptides with a suitable physicochemical transducer, with the final aim of providing a direct reading of the levels of a specific analyte in the sample. This technology seeks to facilitate point-of-care diagnostics, bringing the clinical laboratory to the doctor or the patient.

This Special Issue will provide an overview of the most recent developments in the design of biosensing platforms for clinical applications. Regardless of what combination of recognition element/signal transduction is employed, research articles and reviews focused on devices useful for non-invasive or minimally invasive measurement of analytes in biofluids are welcome. Biosensors that are at multiple stages of development and even in the commercialization pathway can be presented, thus, providing an idea of the multiple opportunities in this field.

Prof. Dr. María Jesús Lobo-Castañón
Guest Editor

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