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Wearable and AI-Driven Sensing for Brain Disorders: From Digital Biomarkers to Clinical Translation

A special issue of Sensors (ISSN 1424-8220). This special issue belongs to the section "Biomedical Sensors".

Deadline for manuscript submissions: 31 October 2026 | Viewed by 309

Special Issue Editors


E-Mail Website
Guest Editor Assistant
Institut de Neurosciences des Systèmes (INS, UMR1106), Marseille, France
Interests: wearable sensing; longitudinal modelling; clinical neuroscience

Special Issue Information

Dear Colleagues,

In the 21st century, brain health has become central to human wellbeing and productivity. As societies shift toward knowledge-based and cognitively demanding activities, maintaining optimal brain function is essential for both individual health and societal sustainability. Consequently, there is an urgent need to strengthen research on brain disorders—including neurodegenerative diseases (e.g., Parkinson’s disease), mental health conditions (e.g., depression), and neurological disorders (e.g., stroke)—which pose major global challenges due to their increasing prevalence and socioeconomic burden.

Recent advances in wearable sensing technologies and artificial intelligence (AI) offer transformative opportunities for understanding and managing brain disorders. Wearable sensors enable continuous, non-invasive, and objective monitoring of behavioral and physiological functions in daily life, capturing subtle functional changes beyond the limits of traditional clinical assessments. When combined with AI-driven analytics, these technologies pave the way for early diagnosis, personalized therapeutic strategies, and remote, continuous care.

This Special Issue aims to present and disseminate the most recent original research and comprehensive reviews related to wearable sensor systems and AI-based methods applied to brain disorders. We welcome contributions that demonstrate the clinical applicability of wearable sensors, integration with AI for diagnostic or therapeutic purposes, and evidence-based validation in patient populations and real-world contexts.

Topics of interest for publication include, but are not limited to, the following:

- hardware design and innovation;
- signal processing;
- digital biomarkers;
- data privacy and ethics;
- human–technology interaction;
- AI-based modeling;
- clinical validation;
- real-world translation

Dr. Cristina P. Santos
Guest Editor

Dr. Cristiana Filipa Sampaio Pinheiro
Guest Editor Assistant

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Sensors is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • artificial intelligence
  • brain disorders
  • continuous monitoring
  • digital biomarkers
  • early diagnosis
  • personalized therapies
  • wearable sensors

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Published Papers

This special issue is now open for submission.
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