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Special Issue "Repeated or Continuous Glucose Monitoring: Sensors, Devices and Applications"

A special issue of Sensors (ISSN 1424-8220). This special issue belongs to the section "Biosensors".

Deadline for manuscript submissions: 20 October 2019

Special Issue Editor

Guest Editor
Dr. Andrea Tura

Metabolic Unit, Institute of Neuroscience, National Research Council, Corso Stati Uniti 4, 35127 Padova, Italy
Website | E-Mail
Interests:
• Analysis of sequences of data, with special interest to Continuous Glucose Monitoring data (CGM) for the estimation of glycemic control and glycemic variability
• Glucose monitoring through non-invasive techniques, with special focus on electro-impedance spectroscopy approach
• Monitoring of glucose and sodium concentration during dialysis, through electro-impedance spectroscopy coupled with ion-exchange resins
• Mathematical models and methods for quantitative physiology and quantitative clinical tests, particularly in the field of chronic diseases, such as Type 2 Diabetes and related cardiovascular diseases. Special interest is on models of pancreatic beta-cell function and insulin sensitivity
• Telemedicine for home monitoring of subjects requiring continuous, non-ending health care, based on the use of portable and wearable medical instruments

Special Issue Information

Dear Colleagues,

In recent years, glucose monitoring has been revolutionized by the development of continuous glucose monitoring (CGM) sensors, and wearable non/minimally-invasive devices that measure glucose concentration by exploiting different physical principles, e.g., glucose-oxidase, fluorescence, or skin dielectric properties, and provide real-time measurements every 1 to 5 min. Continuous glucose monitoring presented new challenges in different disciplines, e.g., medicine, physics, electronics, chemistry, ergonomics, data/signal processing, and software development. It has been an important component in improving outcomes in patients with type 1 and type 2 diabetes, but also with gestational diabetes and other metabolic diseases. Advances have also been recently achieved in the technology of traditional glucose meters for self-monitoring of blood glucose (SMBG), which, compared to the CGM device, has the advantage of measuring glucose directly in blood.

In this Special Issue, we seek unique research and development efforts, exploring technologies for glucose sensors and their applications, especially for people with metabolic diseases. Other fields of application of glucose sensors are also considered. In more detail, particular topics of interest include, but are not limited to, the following:

  • Glucose sensors and meters for self-monitoring of blood glucose (SMBG);
  • Continuous glucose monitoring (CGM) sensors and meters;
  • Flash glucose monitoring (FGM) sensors;
  • Non-invasive glucose monitoring sensors;
  • Implantable glucose sensors;
  • Flexible glucose sensors;
  • Smart fabric/electronic textile glucose sensors;
  • Tools and methodologies for analysis of data from glucose sensors;
  • Glucose sensors in food science;
  • Glucose sensors for veterinary use.

Dr. Andrea Tura
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Sensors is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Published Papers (1 paper)

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Research

Open AccessArticle Low-Temperature Storage Improves the Over-Time Stability of Implantable Glucose and Lactate Biosensors
Sensors 2019, 19(2), 422; https://doi.org/10.3390/s19020422
Received: 21 December 2018 / Revised: 9 January 2019 / Accepted: 18 January 2019 / Published: 21 January 2019
PDF Full-text (1734 KB) | HTML Full-text | XML Full-text | Supplementary Files
Abstract
Molecular biomarkers are very important in biology, biotechnology and even in medicine, but it is quite hard to convert biology-related signals into measurable data. For this purpose, amperometric biosensors have proven to be particularly suitable because of their specificity and sensitivity. The operation [...] Read more.
Molecular biomarkers are very important in biology, biotechnology and even in medicine, but it is quite hard to convert biology-related signals into measurable data. For this purpose, amperometric biosensors have proven to be particularly suitable because of their specificity and sensitivity. The operation and shelf stability of the biosensor are quite important features, and storage procedures therefore play an important role in preserving the performance of the biosensors. In the present study two different designs for both glucose and lactate biosensor, differing only in regards to the containment net, represented by polyurethane or glutharaldehyde, were studied under different storage conditions (+4, −20 and −80 °C) and monitored over a period of 120 days, in order to evaluate the variations of kinetic parameters, as VMAX and KM, and LRS as the analytical parameter. Surprisingly, the storage at −80 °C yielded the best results because of an unexpected and, most of all, long-lasting increase of VMAX and LRS, denoting an interesting improvement in enzyme performances and stability over time. The present study aimed to also evaluate the impact of a short-period storage in dry ice on biosensor performances, in order to simulate a hypothetical preparation-conservation-shipment condition. Full article
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