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Electrochemiluminescence Sensing and Detection System

A special issue of Sensors (ISSN 1424-8220). This special issue belongs to the section "Chemical Sensors".

Deadline for manuscript submissions: closed (10 October 2023) | Viewed by 5772

Special Issue Editor


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Guest Editor
Department of Chemistry and Biochemistry, Creighton University, Omaha, NE 68178, USA
Interests: electrochemistry; carbon; electrochemiluminescence; electrogenerated chemiluminescence; biosensors; chemical sensors

Special Issue Information

Dear Colleagues, 

Electrochemiluminescent (ECL) sensing and detection is an exciting field with many applications in environmental and biomedical analysis. In addition to these topics, a significant amount exciting fundamental research is being carried out into ECL mechanisms and novel ECL emitters and materials. ECL methods are sensitive and can be applied to laboratory analysis but are also amenable to portable and inexpensive detection methods. Topics and applications may include but are not limited to biosensors, novel electrode and ECL materials, novel electroluminescent species, reaction mechanism investigation, microscale, portable and microfluidic devices, and clinical and environmental applications.

As a Guest Editor, I cordially invite you to submit a manuscript for consideration and possible publication in a Special Issue on “Electrochemiluminescence Sensing and Detection System” to be published in the journal Sensors, a leading international, peer-reviewed, open access journal on the science and technology of sensors. Sensors is published semimonthly online by MDPI and is indexed in the Science Citation Index Expanded (Web of Science), with a 2020 impact factor of 3.576. 

Prof. Dr. Erin M. Gross
Guest Editor

Manuscript Submission Information

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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • electrochemiluminescence
  • luminescence
  • biosensors
  • electrodes
  • microscale
  • biosensors
  • nanomaterials
  • mechanisms
  • microfluidics

Published Papers (3 papers)

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Research

14 pages, 2373 KiB  
Article
Comparison of Mobile Phone and CCD Cameras for Electrochemiluminescent Detection of Biogenic Amines
by Nic Heckenlaible, Sarah Snyder, Patrick Herchenbach, Alyssa Kava, Charles S. Henry and Erin M. Gross
Sensors 2022, 22(18), 7008; https://doi.org/10.3390/s22187008 - 16 Sep 2022
Cited by 2 | Viewed by 1719
Abstract
Biogenic amines are an important and widely studied class of molecules due to their link to the physiological processes of food-related illnesses and histamine poisoning. Electrochemiluminescent (ECL) detection offers an inexpensive and portable analytical method of detection for biogenic amines when coupled with [...] Read more.
Biogenic amines are an important and widely studied class of molecules due to their link to the physiological processes of food-related illnesses and histamine poisoning. Electrochemiluminescent (ECL) detection offers an inexpensive and portable analytical method of detection for biogenic amines when coupled with recent advancements in low-cost carbon-based electrodes and a smartphone camera. In this work, a mobile phone camera was evaluated against a piece of conventional instrumentation, the charge-coupled device, for the detection of ECL from the reaction of biogenic amines with the luminescent compound tris(2,2′-bipyridyl)ruthenium(II). Assisted by a 3D-printed light-tight housing, the mobile phone achieved limits of detection of 127, 425 and 421 μM for spermidine, putrescine, and histamine, respectively. The mobile phone’s analytical figures of merit were lesser than the CCD camera but were still within the range to detect contamination. In an exploration of real-world samples, the mobile phone was able to determine the contents of amines in skim milk on par with that of a CCD camera. Full article
(This article belongs to the Special Issue Electrochemiluminescence Sensing and Detection System)
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14 pages, 2847 KiB  
Article
One-Step Fabrication of Highly Sensitive Tris(2,2′-bipyridyl)ruthenium(II) Electrogenerated Chemiluminescence Sensor Based on Graphene-Titania-Nafion Composite Film
by Sang Jung Lee, Don Hui Lee and Won-Yong Lee
Sensors 2022, 22(8), 3064; https://doi.org/10.3390/s22083064 - 15 Apr 2022
Viewed by 1586
Abstract
A highly sensitive tris(2,2′-bipyridyl)ruthenium(II) (Ru(bpy)32+) electrogenerated chemiluminescence (ECL) sensor based on a graphene-titania-Nafion composite film has been prepared in a simple one-step manner. In the present work, a highly concentrated 0.1 M Ru(bpy)32+ solution was mixed with an [...] Read more.
A highly sensitive tris(2,2′-bipyridyl)ruthenium(II) (Ru(bpy)32+) electrogenerated chemiluminescence (ECL) sensor based on a graphene-titania-Nafion composite film has been prepared in a simple one-step manner. In the present work, a highly concentrated 0.1 M Ru(bpy)32+ solution was mixed with an as-prepared graphene-titania-Nafion composite solution (1:20, v/v), and then a small aliquot (2 µL) of the resulting mixture solution was cast on a glassy carbon electrode surface. This one-step process for the construction of an ECL sensor shortens the fabrication time and leads to reproducible ECL signals. Due to the synergistic effect of conductive graphene and mesoporous sol-gel derived titania-Nafion composite, the present ECL sensor leads to a highly sensitive detection of tripropylamine from 1.0 × 10−8 M to 2.0 × 10−3 M with a detection limit of 0.8 nM (S/N = 3), which is lower in comparison to that of the ECL sensor based on the corresponding ECL sensor based on the titania-Nafion composite containing carbon nanotube. The present ECL sensor also shows a good response for nicotinamide adenine dinucleotide hydrogen (NADH) from 1.0 × 10−6 M to 1.0 × 10−3 M with a detection limit of 0.4 µM (S/N = 3). Thus, the present ECL sensor can offer potential benefits in the development of dehydrogenase-based biosensors. Full article
(This article belongs to the Special Issue Electrochemiluminescence Sensing and Detection System)
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10 pages, 2896 KiB  
Article
Highly Sensitive Detection of the Insecticide Azamethiphos by Tris(2,2′-bipyridine)ruthenium(II) Electrogenerated Chemiluminescence
by Tesfaye Hailemariam Barkae, Abdallah M. Zeid and Guobao Xu
Sensors 2022, 22(7), 2519; https://doi.org/10.3390/s22072519 - 25 Mar 2022
Viewed by 1964
Abstract
Azamethiphos (AZA) is an insecticide and neurotoxic agent that causes the inhibition of acetylcholinesterase (AChE). AChE is a vital enzyme for neurotransmission because it metabolizes acetylcholine neurotransmitter at the synaptic cleft and terminates synaptic transmission. It is worth mentioning that organophosphates and carbamates [...] Read more.
Azamethiphos (AZA) is an insecticide and neurotoxic agent that causes the inhibition of acetylcholinesterase (AChE). AChE is a vital enzyme for neurotransmission because it metabolizes acetylcholine neurotransmitter at the synaptic cleft and terminates synaptic transmission. It is worth mentioning that organophosphates and carbamates inhibit AChE. These AChE inhibitors bind to the active site of the enzyme and inactivate it, leading to paralysis and death. Herein, for the first time, we develop a sensitive, low-cost, and rapid electrogenerated chemiluminescence (ECL) system for the detection of AZA. The designed ECL sensor was applied for the highly sensitive detection of AZA with a wide dynamic range (from 0.1 μM to 1000 μM) and low detection limit of 0.07 μM (S/N = 3). The practical utility of the sensor demonstrates high recoveries (96–102%) in real samples of lake water and wastewater. Full article
(This article belongs to the Special Issue Electrochemiluminescence Sensing and Detection System)
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