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Advanced Biosensors for Foodborne Pathogens

A special issue of Sensors (ISSN 1424-8220). This special issue belongs to the section "Biosensors".

Deadline for manuscript submissions: closed (28 July 2023) | Viewed by 4965

Special Issue Editors

State Key Laboratory of Transducer Technology, Shanghai Institute of Microsystem and Information Technology, Chinese Academy of Sciences, Shanghai 200050, China
Interests: microfluidics; biosensor; magnetic separation; foodborne pathogen; POCT device
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Key Laboratory of Agricultural Information Acquisition Technology, Ministry of Agriculture and Key Laboratory of Modern Precision Agriculture System Integration Research, Ministry of Education, China Agricultural University, Beijing 100083, China
Interests: biosensors; microfluidic chips; magnetic separation; food safety; animal disease control
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
School of Food and Health, Beijing Technology and Business University (BTBU), Beijing, 100048, PR China
Interests: biosensor; immunoassay; nanomaterials; microfluidic chip; food safety
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Food safety is one of the most significant issues of people’s livelihood and the national economy. Rapid screening of foodborne pathogens is the key to ensure food safety. Biosensor research has undergone rapid growth in recent years, giving new concepts in biomarker recognition, miniaturization, and multiplex analysis in food safety. In addition, microfluidics and some other micro- and nano-devices provides new strategies to improve the applicability of biosensors for in-field detection. This Special Issue will provide an opportunity for researchers to publish their original achievements related to the biosensors for foodborne pathogens.

The Special Issue welcomes both original research and review articles that address the following non-exhaustive list of topics:

  • Novel pretreatment and enrichment methods for food samples;
  • Novel sensing elements;
  • Signal amplification strategies;
  • Novel nanomaterials with controllable characteristics;
  • Microfluidic or Sample-in-Result-out system.

Dr. Gaozhe Cai
Prof. Dr. Jianhan Lin
Dr. Lingyan Zheng
Guest Editors

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Keywords

  • biosensor
  • foodborne pathogens
  • nanomaterials
  • microfluidics
  • sample pretreatment
  • signal amplification 
  • portable devices 
  • rapid detection

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Published Papers (2 papers)

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Research

12 pages, 2867 KiB  
Article
One-Pot Synthesis of Enzyme and Antibody/CaHPO4 Nanoflowers for Magnetic Chemiluminescence Immunoassay of Salmonella enteritidis
by Xingchu Mao and Ranfeng Ye
Sensors 2023, 23(5), 2779; https://doi.org/10.3390/s23052779 - 3 Mar 2023
Cited by 4 | Viewed by 1879
Abstract
In this study, through a bioinspired strategy, the horseradish peroxidase (HRP) and antibody (Ab) were co-embedded into CaHPO4 to prepare HRP-Ab-CaHPO4 (HAC) bifunctional hybrid nanoflowers by one-pot mild coprecipitation. The as-prepared HAC hybrid nanoflowers then were utilized as the signal tag [...] Read more.
In this study, through a bioinspired strategy, the horseradish peroxidase (HRP) and antibody (Ab) were co-embedded into CaHPO4 to prepare HRP-Ab-CaHPO4 (HAC) bifunctional hybrid nanoflowers by one-pot mild coprecipitation. The as-prepared HAC hybrid nanoflowers then were utilized as the signal tag in a magnetic chemiluminescence immunoassay for application in the detection of Salmonella enteritidis (S. enteritidis). The proposed method exhibited excellent detection performance in the linear range of 10–105 CFU/mL, with the limit of detection (LOD) of 10 CFU/mL. This study indicates great potential in the sensitive detection of foodborne pathogenic bacteria in milk with this new magnetic chemiluminescence biosensing platform. Full article
(This article belongs to the Special Issue Advanced Biosensors for Foodborne Pathogens)
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11 pages, 1790 KiB  
Communication
Simulation of Rapid Thermal Cycle for Ultra-Fast PCR
by Zhuo Yang, Jiali Zhang, Xin Tong, Wenbing Li, Lijuan Liang, Bo Liu and Chang Chen
Sensors 2022, 22(24), 9990; https://doi.org/10.3390/s22249990 - 18 Dec 2022
Cited by 3 | Viewed by 2331
Abstract
The polymerase chain reaction (PCR) technology is a mainstream detection method used in medical diagnoses, environmental monitoring, food hygiene, and safety. However, the systematic analysis of a compact structure with fast temperature changes for an ultra-fast PCR device that is convenient for on-site [...] Read more.
The polymerase chain reaction (PCR) technology is a mainstream detection method used in medical diagnoses, environmental monitoring, food hygiene, and safety. However, the systematic analysis of a compact structure with fast temperature changes for an ultra-fast PCR device that is convenient for on-site detection still lacks investigation. To overcome the problems of low heating efficiency and non-portability of PCR devices currently used, a miniaturized PCR system based on a microfluidic chip, i.e., lab-on-chip technology, has been proposed. The main objective of this paper is to explore the feasibility of using a heat resistor that can reach a fast heating rate and temperature uniformity combined with air cooling technology for rapid cooling and to investigate the influences of various pattern designs and thicknesses of the resistor on heating rates and temperature uniformity. Additionally, a PCR chip made of various materials with different thermal properties, such as surface emissivity, thermal conductivity, mass density, and heat capacity at constant pressure is analyzed. In addition to the heat loss caused by the natural convection of air, the radiation loss of the simulation object is also considered, which makes the model much closer to the practical situation. Our research results provide a considerable reference for the design of the heating and cooling modules used in the ultra-fast PCR protocol, which has great potential in In Vitro Diagnosis (IVD) and the PCR detection of foodborne pathogens and bacteria. Full article
(This article belongs to the Special Issue Advanced Biosensors for Foodborne Pathogens)
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