Surface-Enhanced Raman Scattering Sensors and Applications: Recent Advancements and Perspectives
A special issue of Sensors (ISSN 1424-8220). This special issue belongs to the section "Nanosensors".
Deadline for manuscript submissions: closed (31 July 2024) | Viewed by 942
Special Issue Editors
Interests: Raman; SERS; nanomaterials; self-assembly; biosensor
Interests: vibrational spectroscopies; surface-enhanced Raman scattering; plasmonics; synthesis and functionalization of nanomaterials; optofluidic biosensing platforms
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Since its early discovery in 1973 and its theorization in 1977, surface-enhanced Raman scattering has been assessed as one of the most powerful effects for the conceptualization and realization of sensitive optical detection systems. Surface-enhanced Raman spectroscopy is a technique with the potential to detect species down to the single molecule level thanks to the tremendous enhancement of the Raman signal at the surface of some nanomaterials, and in particular in the so-called hotspots usually generated by plasmonic nanostructures. Although a comprehensive explanation of the SERS mechanism has not been postulated yet, many SERS systems have been developed and proposed as efficient systems that have found a wide range of applications in chemical sensing, biomedical and environmental analysis, agri-food and cultural heritage studies. The main exploited SERS mechanism is the electromagnetic one, which originates from the localized plasmon resonance field effect that takes place on the surface of metallic nanostructures and in particular of gold and silver nanoparticles. A great variety of SERS sensors are based on these nanomaterials organized in 1D, 2D or 3D structures and fabricated through both top-down and bottom-up approaches. A SERS sensor is either based on the direct molecular signal of the analyte or based on the indirect signal of a Raman reporter molecule attached to the SERS nanostructure. The gain in the Raman signal of the analytes with SERS substrates can reach values as high as 10^10-10^11, and the SERS sensor allows high sensitivity with intrinsic specificity for determining structural information about molecular systems. A major drawback of metallic nanostructured SERS substrates was previously represented by a low reproducibility of the SERS response; however, great efforts in the manufacturing of SERS-active nanomaterials have been made such that reliable and cost-effective SERS sensor devices are now available.
Dr. Martina Banchelli
Dr. Chiara Novara
Guest Editors
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Keywords
- SERS
- nanotechnology
- nanomaterials
- plasmonics
- analytical chemistry
- sensors
- biosensors
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