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Biomedical Sensors for Cardiology

A special issue of Sensors (ISSN 1424-8220). This special issue belongs to the section "Biomedical Sensors".

Deadline for manuscript submissions: 31 December 2024 | Viewed by 1363

Special Issue Editor


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Guest Editor
School of Engineering, Jordanstown Campus, Ulster University, Shore Road, Newtownabbey BT37 0QB, UK
Interests: atrial fibrillation surveillance and solutions with improved QALY outcome difference; highly efficient cordless energy supply systems for implanted artificial heart pumps; connected-health enabled cardiovascular healthcare services
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Special Issue Information

Dear Colleagues,

Technologies in cardiovascular healthcare are rapid developing and becoming more sophisticated, increasing the reliability and feasibility of long-term, continuous, and non-invasive monitoring of the heart’s vital signs using a variety of sensor technologies and complex wireless network systems approaches. These include non-standard sensor placements in stable and convenient anatomical locotions on the body’s surface for long-term ECG rhythm monitoring and hemodynamics surrogate measurements from the arm brachial blood vessels by means of dynamic bioimpedance techniques. In addition, therapeutic devices for the treatment of heart diseases could be temporary, leading to a therapies for permanent diseases or destination devices for a particular heart disease. The latter devices are technologically more challenging, as they usually require an implantable device in long-term operation. Nevertheless, they have an increasing demand due to the global aging population. Thus, biomedical sensors development offers a great opportunity to capture dynamic body-surface vital signs of the heart in real-time and in a nonintrusive and continuous mode. Moreover, new biocompatible materials in the development of tissue engineering enable advanced cardiovascular therapeutics destination devices.

   Overall Scope:

  • Wearable biocompatible dry ECG electrodes for long-term monitoring.
  • Wearable armbands for long-term ECG and impedance cardiography (ICG) monitoring methods.
  • Biocompatible materials in tissue engineering and sensors, enabling advanced cardiovascular therapeutics destination devices.

Prof. Dr. Omar Escalona
Guest Editor

Manuscript Submission Information

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Keywords

  • long-term vital signs monitoring
  • wearable biocompatible dry ECG electrodes
  • body-surface surrogate cardiac contractility monitoring techniques
  • noninvasive sensors
  • cardiovascular therapeutic destination implanted devices
  • tissue engineering solutions in cardiology

Published Papers (1 paper)

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Research

17 pages, 11131 KiB  
Article
A Flexible PDMS-Based Optical Biosensor for Stretch Monitoring in Cardiac Tissue Samples
by Andrea Sannino, Antonio Velarte, Aránzazu Otín, José Ignacio Artigas and Aida Oliván-Viguera
Sensors 2023, 23(23), 9454; https://doi.org/10.3390/s23239454 - 28 Nov 2023
Viewed by 1039
Abstract
Cardiotoxicity, characterized by adverse impacts on normal heart function due to drug exposure, is a significant concern due to the potentially serious side effects associated with various pharmaceuticals. It is essential to detect the cardiotoxicity of a drug as early as possible in [...] Read more.
Cardiotoxicity, characterized by adverse impacts on normal heart function due to drug exposure, is a significant concern due to the potentially serious side effects associated with various pharmaceuticals. It is essential to detect the cardiotoxicity of a drug as early as possible in the testing phase of a medical composite. Therefore, there is a pressing need for more reliable in vitro models that accurately mimic the in vivo conditions of cardiac biopsies. In a functional beating heart, cardiac muscle cells are under the effect of static and cyclic stretches. It has been demonstrated that cultured cardiac biopsies can benefit from external mechanical loads that resemble the in vivo condition, increasing the probability of cardiotoxicity detection in the early testing stages. In this work, a biosensor is designed and fabricated to allow for stretch monitoring in biopsies and tissue cultures using an innovative sensing mechanism. The detection setup is based on a biocompatible, thin, flexible membrane—where the samples are attached—which is used as an optical waveguide to detect pressure-caused shape changes and stretches. Various prototypes have been fabricated with a cost-effective process, and different measurements have been carried out to experimentally validate the proposed measurement technique. From these evaluations, stretches of up to 1.5% have been measured, but the performed simulations point towards the possibility of expanding the considered technique up to 10–30% stretches. Full article
(This article belongs to the Special Issue Biomedical Sensors for Cardiology)
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