Advances in Developmental Neuroscience and Psychiatry: Integrating Cognitive Science and Mental Health

A special issue of Psychiatry International (ISSN 2673-5318). This special issue belongs to the section "Developmental Psychiatry and Early-Life Mental Health".

Deadline for manuscript submissions: 28 February 2027 | Viewed by 1316

Editors


E-Mail Website
Guest Editor

Special Issue Information

Dear Colleagues,

Research on the developmental origins of mental health and psychopathology has grown rapidly over the past two decades, driven by advances in developmental neuroscience, psychology, cognitive science, and psychiatry. A substantial body of literature has documented age-related changes in brain structure and function, identified the psychological and cognitive risk factors, and described the developmental trajectories of psychiatric disorders. However, much of this work remains compartmentalized within disciplinary traditions, often emphasizing either neural mechanisms or psychological processes in isolation. As a result, existing accounts frequently fall short of explaining how dynamic interactions between brain maturation, cognitive development, and lived experience jointly shape mental health outcomes across development. This fragmentation limits both theoretical progress and the translation of developmental science into clinically meaningful applications.

This Special Issue is motivated by the need for a more integrative developmental perspective that consolidates insights across levels of analysis and moves beyond descriptive associations toward a mechanistic and translational understanding. Its scientific relevance lies in explicitly bridging the fields of developmental neuroscience, psychology, and psychiatry to clarify how neurodevelopmental processes interact with cognitive, emotional, and social development to confer risk for—or protection against—psychopathology.

We invite high-quality empirical, theoretical, and review contributions from the fields of developmental neuroscience, psychology, cognitive science, and psychiatry. Rapid advances in neural imaging, developmental psychology, and computational cognitive modeling are reshaping our understanding of how brain maturation and psychological processes jointly influence mental health trajectories across the lifespan. At the same time, emerging methodologies and longitudinal designs offer unprecedented opportunities to examine how early experiences, biological sensitivity, and environmental contexts become embedded in developing neural and cognitive systems. However, despite these advances, integrative models that connect neural, psychological, and clinical levels of analysis remain underdeveloped, leaving significant opportunities for synthesis, conceptual innovation, and methodological convergence.

We seek manuscripts that advance this integration by addressing topics such as the following:

  • Neurodevelopmental mechanisms underlying cognitive, emotional, and social development, and the implications these mechanisms have for psychological functioning and psychiatric vulnerability across childhood, adolescence, and emerging adulthood.
  • Psychological and cognitive models—including developmental, social, cognitive, and clinical psychology—that elucidate how early experiences, learning processes, and social contexts interact with brain development to shape mental health trajectories.
  • Translational research that connects neural, psychological, and cognitive findings for prevention, assessment, and intervention strategies, with particular emphasis on sensitive developmental periods and mechanisms of change.
  • Biomarkers and methodological innovations (e.g., neuroimaging, genetics, digital phenotyping, behavioral analytics, computational modeling) that enhance early detection, risk stratification, or personalized treatment approaches.
  • Integrated developmental frameworks that bridge psychology, neuroscience, and psychiatry to reconceptualize diagnostic boundaries, developmental pathways to disorder, and developmentally informed therapeutic strategies.

By bringing together researchers and clinicians across developmental psychology, cognitive neuroscience, and clinical psychiatry, this Special Issue seeks to clarify how developing neural and cognitive systems contribute to the emergence, maintenance, and modification of psychopathology. Importantly, the integrative perspective advanced in this Special Issue is not only intended to refine theory, but also to enhance the precision of diagnostic practices and support the development of developmentally informed, evidence-based interventions for children, adolescents, and young adults.

Dr. Vanja Kopilaš
Dr. Lovorka Brajković
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Psychiatry International is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1200 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • developmental neuroscience
  • developmental psychology
  • cognitive science
  • psychiatry
  • neurodevelopment
  • mental health

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.

Further information on MDPI's Special Issue policies can be found here.

Published Papers (2 papers)

Order results
Result details
Select all
Export citation of selected articles as:

Research

14 pages, 276 KB  
Article
Performance-Based Personality Functioning and Long-Term Outcome in Hospitalized Women with Depression: A Four-Year Follow-Up
by Sana Čoderl Dobnik, Sinja Babič Miloševič and Jurij Bon
Psychiatry Int. 2026, 7(4), 160; https://doi.org/10.3390/psychiatryint7040160 - 16 Jul 2026
Abstract
Background: Depression is among the most prevalent psychiatric conditions and markedly disrupts everyday functioning. Its origins are multifactorial, with biological, psychological, and contextual influences jointly shaping the course of recovery and the response to treatment. Personality has been proposed as a relatively stable [...] Read more.
Background: Depression is among the most prevalent psychiatric conditions and markedly disrupts everyday functioning. Its origins are multifactorial, with biological, psychological, and contextual influences jointly shaping the course of recovery and the response to treatment. Personality has been proposed as a relatively stable factor that may reflect developmental influences on emotional and cognitive functioning and may be associated with long-term clinical outcomes in depression. The present study aimed to examine the association between implicit personality characteristics in women hospitalized for depressive disorder and their long-term psychosocial functioning, using a performance-based measure of personality (the Rorschach Inkblot Method, RIM). Subjects and Methods: At baseline (T1), 58 women hospitalized for depressive disorder completed the Beck Depression Inventory (BDI-II) and the Rorschach Inkblot Method (RIM); Rorschach protocols were scored using the Ego Impairment Index—second revision (EII-2), a behaviorally derived index spanning perceptual accuracy, executive integrity, and social cognition. Demographic and clinical information was abstracted from medical records, and an independent rating of functioning was obtained with the Global Assessment of Functioning scale (GAF). Four years later (T2), patients were re-administered the BDI-II and the GAF, and major life events occurring during the follow-up interval were quantified with the Social Readjustment Rating Scale (SRRS). Results: Baseline implicit personality organization showed a significant association with psychosocial functioning four years after the index hospitalization. Among the variables examined, personality structure at admission outperformed both initial depressive symptom severity and the burden of intervening life events in predicting later functional status. In particular, EII-2 accounted for an additional 10.3% of the variance (ΔR2 = 0.103, p < 0.05) over and above age, chronicity, stress, and depressive symptom severity when predicting four-year GAF-rated functioning. Among the predictors examined, age was the most influential variable in the final model (β = 0.442), indicating that demographic factors carry substantial weight alongside personality functioning in shaping long-term outcomes. Conclusions: Our findings are consistent with the view that a patient’s personality may influence the course of recovery and suggest that personality-level factors deserve attention when planning care for this clinically complex disorder. The present results indicate that implicit cognitive–perceptual features—assessed through performance-based methods that bypass conscious self-report—may be associated with long-term psychosocial functioning in women hospitalized for depression. These findings suggest that performance-based personality assessment deserves further study as a potential prognostic aid, although replication in larger and more diverse samples is needed before clinical application. Full article
Show Figures

Graphical abstract

17 pages, 464 KB  
Article
Psychiatric and Functional Outcomes in Preterm School-Aged Children in Greece
by Symeon Dimitrios Daskalou, Theodoros N. Sergentanis, Nikolaos Gerosideris, Christina Ouzouni, Elpida Stratou and Ioanna Giannoula Katsouri
Psychiatry Int. 2026, 7(3), 92; https://doi.org/10.3390/psychiatryint7030092 - 1 May 2026
Viewed by 955
Abstract
Background: Preterm birth is a significant early-life stressor associated with increased psychiatric vulnerability and long-term functional impairments in school-aged children. Objective: To compare behavioral–emotional outcomes and functional competence between school-aged preterm and term-born children, examining perinatal, cognitive, and socioeconomic predictors. Methods: 140 children [...] Read more.
Background: Preterm birth is a significant early-life stressor associated with increased psychiatric vulnerability and long-term functional impairments in school-aged children. Objective: To compare behavioral–emotional outcomes and functional competence between school-aged preterm and term-born children, examining perinatal, cognitive, and socioeconomic predictors. Methods: 140 children aged 6–10 (70 preterm, 70 age-matched controls) were assessed using the Child Behavior Checklist (CBCL) and Strengths and Difficulties Questionnaire (SDQ). Functional competence—defined as participation in daily activities, social interactions, and school performance—was examined alongside behavioral–emotional outcomes. Predictors included gestational age, birth weight, SES, and cognitive ability. Results: Preterm birth was associated with higher SDQ scores in emotional problems, hyperactivity, and peer problems. CBCL results showed lower total functional competence scores, specifically in activities, social participation, and school performance. Longer NICU stay predicted higher internalizing problems and lower social participation. Cognitive ability was linked to lower SDQ externalizing and internalizing scores. SES was not a significant predictor. Conclusions: Preterm birth and prolonged NICU hospitalization are linked to persistent behavioral–emotional and functional vulnerabilities. These findings underscore the need for early, integrated developmental monitoring within a preventive psychiatry framework to identify psychiatric vulnerability and support functional participation. Full article
Show Figures

Figure 1

Back to TopTop