Proteomics in Diabetes: From Mechanisms to Biomarkers
A special issue of Proteomes (ISSN 2227-7382). This special issue belongs to the section "Proteomics of Human Diseases and Their Treatments".
Deadline for manuscript submissions: 31 May 2026 | Viewed by 997
Special Issue Editor
Special Issue Information
Dear Colleagues,
Type 2 diabetes is a complex and heterogeneous disease driven by diverse molecular alterations across multiple tissues. Despite advances in our understanding of its pathogenesis, key mechanisms remain unclear, and there is a critical need for robust biomarkers to improve diagnosis, risk stratification, and treatment response monitoring. Proteomics offers unique insights into the dynamic protein networks underlying insulin resistance, beta-cell dysfunction, and systemic metabolic dysregulation.
For this Special Issue of Proteomes, we welcome original research articles and reviews that explore how proteomic technologies can advance our understanding of diabetes—from unraveling disease mechanisms to identifying clinically relevant biomarkers. We are particularly interested in studies that use advanced mass spectrometry, spatial proteomics, or integrative multi-omics approaches to investigate protein expression, modifications, interactions, or localization in tissues relevant to diabetes, such as pancreas, liver, muscles, adipose tissue, or blood.
Submissions from both clinical and preclinical research are welcome, with a focus on human studies, but animal models may also be relevant. We also encourage contributions that focus on proteomic signatures of diabetes complications, therapeutic targets, or the development of diagnostic or prognostic tools. Studies showcasing methodological innovations that enhance the sensitivity, specificity, or interpretability of proteomic data in the context of diabetes are also of high interest.
Dr. Sindre Lee-Ødegård
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Proteomes is an international peer-reviewed open access quarterly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- proteomics
- diabetes mellitus
- insulin resistance
- biomarkers
- pathophysiology
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