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Advancements in Polymeric Materials for Precision Drug Delivery

A special issue of Polymers (ISSN 2073-4360). This special issue belongs to the section "Polymer Applications".

Deadline for manuscript submissions: 31 October 2026 | Viewed by 58

Special Issue Editor


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Guest Editor
Marine Biomedical Research Institute of Qingdao, Ocean University of China, Qingdao, China
Interests: polymer materials; drug delivery system; patient-focused drug development; hot-melt extrusion; 3D printing
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Special Issue Information

Dear Colleagues,

Precision medicine represents the future of medical development, as it has the potential to revolutionize the prevention, diagnosis, and treatment of diseases by shifting medical care from a one-size-fits-all approach for the "average patient" to personalized treatment. Precision drug delivery is the key pathway for achieving personalized precision medicine, and polymeric drug-carrying systems have emerged as the cornerstone of modern precision drug delivery. They offer unparalleled versatility in tailoring therapeutic payloads for site-specific targeting, controlled release and enhanced biocompatibility. These materials are redefining the paradigm of drug formulation and clinical translation, from overcoming biological barriers to enabling personalized treatment regimens. A critical aspect of optimizing efficacy and ensuring patient safety is understanding the structure–function relationship of polymers, their physicochemical interactions with therapeutic agents, and their performance under physiological conditions.

This Special Issue aims to provide a comprehensive overview of recent breakthroughs and future directions in polymeric systems for precision drug delivery. Our goal is to bridge the gap between fundamental material science, formulation engineering, and clinical application by showcasing novel experimental techniques, advanced characterization methods, and cutting-edge computational simulations that advance our understanding of polymeric delivery systems and their impact on therapeutic outcomes.

Potential topics:

  1. Novel polymeric materials and formulation design
  • Synthesis and characterization of stimuli-responsive polymers for on-demand drug release;
  • Engineering of biodegradable and biocompatible polymeric carriers for long-term therapy;
  • Rational design of polymer–drug conjugates with improved pharmacokinetics.
  1. Targeting strategies and biological interactions
  • Ligand-functionalized polymeric systems for active targeting of diseased cells/tissues;
  • Polymeric carriers for overcoming biological barriers;
  • Immunological responses and biocompatibility evaluation of polymeric delivery systems.
  1. Advanced fabrication and processing technologies
  • Fabrication of polymeric micro/nanoparticles for high-throughput drug encapsulation;
  • 3D printing and additive manufacturing of personalized polymeric drug delivery devices;
  • Scalable production techniques for clinical translation of polymeric formulations.
  1. Computational modeling and predictive design
  • Multiscale modeling of polymeric system assembly and drug release kinetics;
  • In silico prediction of polymer–bio membrane interactions and toxicity;
  • Machine learning approaches for optimizing polymeric formulation parameters.

For this Special Issue, researchers and experts are invited to submit original articles, reviews and perspectives on these topics, taking an interdisciplinary approach that combines experimental excellence with computational studies.

Dr. Jiaxiang Zhang
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Polymers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • polymers
  • polymeric delivery systems
  • drug delivery
  • drug release
  • precision medicine
  • 3D printing

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Published Papers

This special issue is now open for submission.
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