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Smart and Functionalized Developments of Polymer-Based Hydrogels

A special issue of Polymers (ISSN 2073-4360). This special issue belongs to the section "Smart and Functional Polymers".

Deadline for manuscript submissions: closed (29 February 2024) | Viewed by 2102

Special Issue Editors


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Guest Editor
School of Rehabilitation Sciences and Engineering, University of Health and Rehabilitation Sciences, Qingdao 266071, China
Interests: hydrogels; tissue repair and regeneration; cell-material interface; antibacterial biomaterials; nanomedicine

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Guest Editor
School of Chemical Engineering, Theranostic Macromolecules Research Center, Sungkyunkwan University, Suwon 16419, Republic of Korea
Interests: hydrogels; drug delivery; carbohydrate polymers; gelation

Special Issue Information

Dear Colleagues,

Polymer-based hydrogels have garnered immense attention due to their remarkable properties and multifaceted applications. This Special Issue aims to gather cutting-edge research contributions that shed light on the design, synthesis, and utilization of smart and functionalized hydrogels. We seek to explore the diverse array of possibilities in the realm of hydrogel applications, spanning from biomedical and environmental applications to advanced functional materials. We hope to deepen our understanding of these materials and their potential for transforming various industries by bringing together leading researchers and their insights. We will provide a comprehensive platform for researchers, academicians, and industry experts to share their knowledge, insights, and discoveries in areas such as novel synthesis and design of smart polymer-based hydrogels; stimuli-responsive hydrogel systems and their applications; functionalization of hydrogels for biomedical and drug delivery purposes; hydrogels for tissue engineering and regenerative medicine; advanced characterization techniques for polymer-based hydrogels; modeling and simulation of hydrogel behavior; prospects and challenges in the field of polymer-based hydrogels.

Prof. Dr. Qihui Zhou
Dr. Thavasyappan Thambi
Guest Editors

Manuscript Submission Information

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Keywords

  • polymer hydrogels
  • smart materials
  • stimuli-responsive
  • biomedical applications
  • environmental applications
  • computational modelling
  • bioactive agents
  • drug delivery
  • tissue engineering
  • biomimetic materials

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Published Papers (1 paper)

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Research

16 pages, 6953 KiB  
Article
Numerical Simulation of Polyacrylamide Hydrogel Prepared via Thermally Initiated Frontal Polymerization
by Xiong Yi, Shengfang Li, Pin Wen and Shilin Yan
Polymers 2024, 16(7), 873; https://doi.org/10.3390/polym16070873 - 22 Mar 2024
Viewed by 1742
Abstract
Traditional polymer curing techniques present challenges such as a slow processing speed, high energy consumption, and considerable initial investment. Frontal polymerization (FP), a novel approach, transforms monomers into fully cured polymers through a self-sustaining exothermic reaction, which enhances speed, efficiency, and safety. This [...] Read more.
Traditional polymer curing techniques present challenges such as a slow processing speed, high energy consumption, and considerable initial investment. Frontal polymerization (FP), a novel approach, transforms monomers into fully cured polymers through a self-sustaining exothermic reaction, which enhances speed, efficiency, and safety. This study focuses on acrylamide hydrogels, synthesized via FP, which hold significant potential for biomedical applications and 3D printing. Heat conduction is critical in FP, particularly due to its influence on the temperature distribution and reaction rate mechanisms, which affect the final properties of polymers. Therefore, a comprehensive analysis of heat conduction and chemical reactions during FP is presented through the establishment of mathematical models and numerical methods. Existing research on FP hydrogel synthesis primarily explores chemical modifications, with limited studies on numerical modeling. By utilizing Differential Scanning Calorimetry (DSC) data on the curing kinetics of polymerizable deep eutectic solvents (DES), this paper employs Malek’s model selection method to establish an autocatalytic reaction model for FP synthesis. In addition, the finite element method is used to solve the reaction–diffusion model, examining the temperature evolution and curing degree during synthesis. The results affirm the nth-order autocatalytic model’s accuracy in studying acrylamide monomer curing kinetics. Additionally, factors such as trigger temperature and solution initial temperature were found to influence the FP reaction’s frontal propagation speed. The model’s predictions on acrylamide hydrogel synthesis align with experimental data, filling the gap in numerical modeling for hydrogel FP synthesis and offering insights for future research on numerical models and temperature control in the FP synthesis of high-performance hydrogels. Full article
(This article belongs to the Special Issue Smart and Functionalized Developments of Polymer-Based Hydrogels)
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