Microalgal Biosynthetic Pathways and Their Modulation: From Basic Knowledge to Biotechnological Applications

A special issue of Phycology (ISSN 2673-9410).

Deadline for manuscript submissions: 31 December 2025 | Viewed by 41

Special Issue Editors


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Guest Editor
Consiglio Nazionale delle Ricerche (CNR), Istituto di Chimica Biomolecolare (ICB), Pozzuoli, Italy
Interests: natural products chemistry; bioactive secondary metabolites; mass spectrometry; lipidomics; structural elucidation; NMR

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Guest Editor
Consiglio Nazionale delle Ricerche, Istituto di Scienze Applicate e Sistemi Intelligenti (ISASI), Pozzuoli, Italy
Interests: molecular biology; marine biology; genetic engeeniring; biotechnology

Special Issue Information

Dear Colleagues,

Microalgae represent a renewable source of valued and specialized metabolites, including polyphenols, terpenoids, polyketides and other functionalized fatty acid-derived lipids, which are of great interest for their functional role and potential biotechnological applications. However, our knowledge of the biosynthetic routes underlying their production remains in some cases quite limited. Cultivation conditions can significantly influence the level of these compounds, modulating gene expression and cellular metabolism; in fact, the modification of physical parameters such as nutrient availability, light intensity, temperature, and salinity has been used as a tool to explore and tune secondary metabolite biosynthesis, particularly in a biotechnological application perspective.

This Special Issue welcomes original contributions and review papers focusing on studies that investigate (1) the effect of cultivation parameters on the biosynthesis and accumulation of specific secondary metabolites and (2) the characterization of biosynthetic pathways involved in their production. By integrating chemical, biochemical, and molecular approaches, it aims to collect recent insights into the regulation and roles of secondary metabolites in microalgae, contributing to the advancement of basic and applied research in this field.

Dr. Adele Cutignano
Dr. Martina Blasio
Guest Editors

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Keywords

  • microalgae
  • secondary metabolites
  • biosynthesis
  • functional lipids
  • biotechnological applications

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This special issue is now open for submission.
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