Optical Imaging Systems in Biomedicine

A special issue of Photonics (ISSN 2304-6732). This special issue belongs to the section "Biophotonics and Biomedical Optics".

Deadline for manuscript submissions: closed (30 November 2023) | Viewed by 2117

Special Issue Editors


E-Mail Website
Guest Editor
School of Optoelectronic Science and Engineering, University of Electronic Science and Technology of China, Chengdu 610054, China
Interests: super-resolution microscopy; single-molecule imaging; spectral imaging; coherent Raman imaging

E-Mail Website
Guest Editor
MIT-Laser Biomedical Research Center, Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
Interests: label-free imaging; optical coherence tomography; quantitative phase microscopy; light-sheet microscopy

Special Issue Information

Dear Colleagues,

Optical imaging, using light and the special properties of photons to obtain detailed images of molecules, organelles, cells, tissues and organs, has emerged as an indispensable tool in life sciences and medicine. In recent decades, the field of optical imaging has seen explosive advancements, with incredible technical breakthroughs, and has attracted significant interest for a broad range of applications, including capturing the in-depth details of biological processes and obtaining valuable information for disease diagnostics.

We are honored to serve as Guest Editors for this Special Issue, entitled “Optical Imaging Systems in Biomedicine”, acknowledging the achievements in this field. This Special Issue aims to report the latest advancements in optical imaging, including, but not limited to, innovative optical imaging techniques and their practical applications in biomedical research, as well as disease diagnosis.

We warmly invite researchers to submit their contributions to this Special Issue, in the form of both original research articles and review papers. Research areas may include (but are not limited to) the following:

  • Fluorescence imaging;
  • Optical coherence tomography (OCT);
  • Nonlinear optical imaging (second harmonic generation, coherent Raman/Brillouin and multiphoton fluorescence microscopy);
  • Photoacoustic tomography and microscopy (PAT and PAM);
  • Diffuse optical tomography and imaging (DOT and DOI);
  • Super-resolution microscopy (STED, PALM/STORM and structured illumination imaging);
  • Light-field microscopy;
  • Phase imaging (quantitative phase microscopy, diffraction phase microscopy, optical diffraction tomography and digital holography microscopy);
  • Light-sheet microscopy (selective plane illumination microscopy);
  • Computational imaging (Fourier ptychography, single-pixel imaging and intensity diffraction tomography);
  • Endoscopy;
  • Bioluminescence imaging;
  • Photothermal microscopy;
  • THz imaging;
  • Adaptive optics in optical imaging systems.

We look forward to receiving your contributions.

Prof. Dr. Kun Chen
Dr. Yuechuan Lin
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Photonics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • optical coherence tomography
  • super-resolution microscopy
  • multiphoton fluorescence microscopy
  • light-sheet microscopy
  • light-field microscopy
  • computational imaging
  • photoacoustic microscopy
  • fluorescence microscopy

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.

Further information on MDPI's Special Issue policies can be found here.

Published Papers (1 paper)

Order results
Result details
Select all
Export citation of selected articles as:

Research

14 pages, 3039 KiB  
Article
Design of a Scanning Module in a Confocal Microscopic Imaging System for Live-Cell Imaging
by Ran Tao and Tao Zhang
Photonics 2024, 11(1), 26; https://doi.org/10.3390/photonics11010026 - 28 Dec 2023
Viewed by 1786
Abstract
This study proposes a Nipkow-based pinhole disk laser scanning confocal microscopic imaging system for ordinary optical microscopy, fluorescence microscopy, and confocal microscopy imaging of biological samples in order to realize the dynamic experimental monitoring of space-based life science experiments and the fine observation [...] Read more.
This study proposes a Nipkow-based pinhole disk laser scanning confocal microscopic imaging system for ordinary optical microscopy, fluorescence microscopy, and confocal microscopy imaging of biological samples in order to realize the dynamic experimental monitoring of space-based life science experiments and the fine observation of biological samples. Confocal microscopic imaging is mainly completed by a scanning module that is composed of a spinning disk and other components. The parameters of the spinning disk directly determine the quality of the image. During the design process, the resolution and signal-to-noise ratios caused by different pinhole diameters in the spinning disk are the main considerations. Changes and image blurring caused by crosstalk due to the pinhole arrangement and different pinhole spacings are addressed. The high photon efficiency of the new EMCCD (electron-multiplying charge-coupled device) and CMOS (complementary metal-oxide-semiconductor) camera reduces the exposure time as much as possible, reduces damage to living cells, and achieves high-speed confocal imaging. It is shown in a confocal imaging experiment with a variable magnification of 1–40× that the imaging resolution of the system can reach a maximum of 2592 × 1944, the spatial resolution can reach 1 μm, and the highest sampling frequency is 10 fps, thus meeting the design requirements for high-speed live-cell imaging. Full article
(This article belongs to the Special Issue Optical Imaging Systems in Biomedicine)
Show Figures

Figure 1

Back to TopTop