Special Issue "Bio-Integrated Photonic Materials and Devices"

A special issue of Photonics (ISSN 2304-6732). This special issue belongs to the section "Biophotonics and Biomedical Optics".

Deadline for manuscript submissions: closed (31 October 2021).

Special Issue Editor

Prof. Dr. Luyao Lu
E-Mail Website
Guest Editor
Department of Biomedical Engineering, The George Washington University, Washington, DC, USA
Interests: flexible/stretchable bioelectronics; photonics; optophysiology; electrophysiology

Special Issue Information

Dear Colleagues,

Biophotonics is a research field utilizing light to interfere with biological subjects such as cells, tissues, and organisms. Recent progress in soft functional materials and device integration strategies have generated numerous flexible and stretchable electronics and greatly advanced many aspects of biophotonics. New bio-integrated photonic sensors and actuators enable broad applications in wearable, implantable, healthcare, and human–machine interfaces, among other areas. In basic biological research, biophotonic technology provides crucial insights into light–cell interactions to better study the basic operating principles of biosystems. In clinical medicine, biophotonics enables the development of important diagnostic and therapeutic approaches.

This Special Issue focuses on presenting original research in bio-integrated photonic materials and devices, with special emphasis on the design and development of soft organic and inorganic photonic materials; flexible/soft optoelectronics; wearable and implantable photonics; as well as their biomedical applications to advance our knowledge and capability in healthcare, brain–machine interfaces, and disease diagnostics/therapeutics. Researchers from interdisciplinary fields such as biomedical engineering, materials science, mechanical engineering, and electrical engineering are invited to submit their contributions to this Special Issue. Topics include but are not limited to the following:

  • Flexible/stretchable bioelectronics;
  • Implantable photonics;
  • Wearable photonics;
  • Biodegradable photonics;
  • Multifunctional optical biointerfaces;
  • Nano-bio photonic interfaces;
  • Biophotonic actuators and sensors;
  • Optical characterizations of biological systems;
  • Bioinspired and biomimetic photonic materials.

Open for submission: around the beginning of 2020

Dr. Luyao Lu
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Photonics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Published Papers (3 papers)

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Research

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Communication
A High-Sensitivity SPR Sensor with Bimetal/Silicon/Two-Dimensional Material Structure: A Theoretical Analysis
Photonics 2021, 8(7), 270; https://doi.org/10.3390/photonics8070270 - 09 Jul 2021
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Abstract
In this paper, we reported a theoretical study of a novel Surface plasmon resonance (SPR) biosensor composed of BK7 prism, gold (Au)/silver (Ag) bimetallic layer, silicon and two-dimensional (2D) materials. The bimetallic layer combines the advantages of Au and Ag and the high [...] Read more.
In this paper, we reported a theoretical study of a novel Surface plasmon resonance (SPR) biosensor composed of BK7 prism, gold (Au)/silver (Ag) bimetallic layer, silicon and two-dimensional (2D) materials. The bimetallic layer combines the advantages of Au and Ag and the high refractive index silicon layer enhances the electric field on the surface of the sensor, so that the sensor has a better overall performance in terms of sensitivity and figure of merit (FOM). Compared with ordinary dielectrics, 2D materials have excellent photoelectric properties, such as larger specific surface area, higher carrier density and stronger adsorption capacity, which improve the detection ability of the sensor. The sensitivity of the optimized sensor achieves 297.2°/RIU, 274°/RIU and 246°/RIU when the silicon layer is covered with graphene, MXene (Ti3T2Cx) and MoS2, respectively. Compared with the traditional SPR sensor, the sensitivity of the structure has been significantly improved, and its excellent performance has broad application prospects in biosensing and other fields. Full article
(This article belongs to the Special Issue Bio-Integrated Photonic Materials and Devices)
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Article
Stretchable and Transparent Metal Nanowire Microelectrodes for Simultaneous Electrophysiology and Optogenetics Applications
Photonics 2021, 8(6), 220; https://doi.org/10.3390/photonics8060220 - 15 Jun 2021
Cited by 1 | Viewed by 731
Abstract
Recently developed optically transparent microelectrode technology provides a promising approach for simultaneous high-resolution electrical and optical biointerfacing with tissues in vivo and in vitro. A critically unmet need is designing high-performance stretchable platforms for conformal biointerfacing with mechanically active organs. Here, we report [...] Read more.
Recently developed optically transparent microelectrode technology provides a promising approach for simultaneous high-resolution electrical and optical biointerfacing with tissues in vivo and in vitro. A critically unmet need is designing high-performance stretchable platforms for conformal biointerfacing with mechanically active organs. Here, we report silver nanowire (Ag NW) stretchable transparent microelectrodes and interconnects that exhibit excellent electrical and electrochemical performance, high optical transparency, superior mechanical robustness and durability by a simple selective-patterning process. The fabrication method allows the direct integration of Ag NW networks on elastomeric substrates. The resulting Ag NW interface exhibits a low sheet resistance (Rsh) of 1.52–4.35 Ω sq−1, an advantageous normalized electrochemical impedance of 3.78–6.04 Ω cm2, a high optical transparency of 61.3–80.5% at 550 nm and a stretchability of 40%. The microelectrode arrays (MEAs) fabricated with this approach exhibit uniform electrochemical performance across all channels. Studies on mice demonstrate that both pristine and stretched Ag NW microelectrodes can achieve high-fidelity electrophysiological monitoring of cardiac activity with/without co-localized optogenetic pacing. Together, these results pave the way for developing stretchable and transparent metal nanowire networks for high-resolution opto-electric biointerfacing with mechanically active organs, such as the heart. Full article
(This article belongs to the Special Issue Bio-Integrated Photonic Materials and Devices)
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Review
Bioresorbable Photonics: Materials, Devices and Applications
Photonics 2021, 8(7), 235; https://doi.org/10.3390/photonics8070235 - 25 Jun 2021
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Abstract
Bio-photonic devices that utilize the interaction between light and biological substances have been emerging as an important tool for clinical diagnosis and/or therapy. At the same time, implanted biodegradable photonic devices can be disintegrated and resorbed after a predefined operational period, thus avoiding [...] Read more.
Bio-photonic devices that utilize the interaction between light and biological substances have been emerging as an important tool for clinical diagnosis and/or therapy. At the same time, implanted biodegradable photonic devices can be disintegrated and resorbed after a predefined operational period, thus avoiding the risk and cost associated with the secondary surgical extraction. In this paper, the recent progress on biodegradable photonics is reviewed, with a focus on material strategies, device architectures and their biomedical applications. We begin with a brief introduction of biodegradable photonics, followed by the material strategies for constructing biodegradable photonic devices. Then, various types of biodegradable photonic devices with different functionalities are described. After that, several demonstration examples for applications in intracranial pressure monitoring, biochemical sensing and drug delivery are presented, revealing the great potential of biodegradable photonics in the monitoring of human health status and the treatment of human diseases. We then conclude with the summary of this field, as well as current challenges and possible future directions. Full article
(This article belongs to the Special Issue Bio-Integrated Photonic Materials and Devices)
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