Advances in Pharmacokinetics of Targeted Anti-Cancer Drugs
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Pharmacokinetics and Pharmacodynamics".
Deadline for manuscript submissions: 20 January 2026 | Viewed by 66
Special Issue Editors
2. Computational BioMedicine Lab, Institute of Computer Science, Foundation for Research & Technology—Hellas, Heraklion, Greece
Interests: pharmacokinetics and pharmacodynamics; PBPK modeling and simulation; drug interactions; computational medicine; in silico pharmacology; pharmacometrics; computational oncology
Special Issues, Collections and Topics in MDPI journals
Interests: cancer drug discovery; breast cancer; prostate cancer; lung cancer; metastasis; cancer stem cells; cancer transcriptomics and proteomics
Special Issue Information
Dear Colleagues,
The ever-evolving field of targeted cancer therapies has significantly reshaped cancer treatment paradigms, offering greater precision and efficacy compared to traditional chemotherapy. Central to this revolution is the advancement of pharmacokinetics (PK) of targeted anti-cancer drugs, which plays a crucial role in optimizing drug delivery, efficacy, and safety profiles. Recent developments in PK studies have provided valuable insights into the absorption, distribution, metabolism, and excretion (ADME) properties of novel targeted agents, thereby informing their clinical use.
Pharmacokinetic modeling and simulation techniques have advanced to predict drug behavior in individual patients, taking into account tumor heterogeneity, molecular targets, and genetic variations. These tools have improved the design of combination therapies and dosing regimens, reducing toxicities while enhancing therapeutic outcomes. Additionally, the integration of biomarkers into PK studies has paved the way for personalized medicine specific to individual patients and tumor subtypes.
Recent innovations in drug delivery systems, such as nanotechnology and antibody–drug conjugates (ADCs), have further advanced PK strategies by enhancing drug specificity and minimizing systemic toxicity. As the field progresses, continued research into the pharmacokinetics of targeted anti-cancer therapies is essential for refining these treatments and improving patient outcomes across diverse cancer types.
Articles reflecting this ethos are welcome for the special edition.
Dr. Marios Spanakis
Dr. Retheesh S. Thankan
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pharmaceutics is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- pharmacokinetics
- targeted anti-cancer drugs
- in vivo models of PK studies
- personalized medicine
- drug design
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- Reprint: MDPI Books provides the opportunity to republish successful Special Issues in book format, both online and in print.
Further information on MDPI's Special Issue policies can be found here.
