Drug Delivery Systems for Asthma and Pulmonary Diseases, 2nd Edition

A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Drug Delivery and Controlled Release".

Deadline for manuscript submissions: 20 December 2024 | Viewed by 233

Special Issue Editors


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Guest Editor
Department of Biochemistry, Faculty of Biology, Universidad Complutense, 28040 Madrid, Spain
Interests: pulmonary surfactant; lung drug delivery; nanoparticles; liposomes; drug-membrane interactions; inhaled drugs; respiratory physiology; lipid/protein interactions; membrane proteins
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Guest Editor
International Medical Center, University of Tsukuba Affiliated Hospital, Tsukuba 305-8576, Japan
Interests: cardiovascular immunology; ischemic insult; nanoparticle development; electron microscopy
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Special Issue Information

Dear Colleagues,

The effect of first-pass metabolism on orally administered medications plus the requirement of solubility to increase absorption limit the effectiveness of various drugs during treatment. For decades, asthmatics have relied on nebulization and aerosols for delivery, but advances in polymerization and nucleic acid packaging have shown promise in the potential of lasting relief being provided by targeted therapies for the epithelial cells involved in asthmatic exacerbations. Other respiratory pathologies (including COVID-19) are benefiting or could also benefit from advanced inhalative therapies. Additionally, the liposomal delivery of therapeutics could increase the local and systemic bioavailability of active ingredients while reducing the effects of first-pass metabolism. Of particular interest is the packaging potential of biopolymers in delivering new therapies derived from monoclonal antibodies, as well as gel- or film-based applications for use in the lungs.

We invite you to submit research on the packaging of asthmatic medications and of drugs targeting other respiratory pathologies, on increases in delivery efficiency, and on the biochemical interactions between target cells and engineered delivery systems.

Prof. Dr. Jesus Perez-Gil
Dr. Bryan Mathis
Guest Editors

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Keywords

  • liposomes
  • nanocarrier
  • pH
  • hydrogel
  • asthma
  • polymeric scaffolds
  • encapsulation
  • solubility
  • microemulsification

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