Cyclodextrins and Associated Nanomaterials for Drug and Gene Delivery

A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Gene and Cell Therapy".

Deadline for manuscript submissions: 15 July 2024 | Viewed by 259

Special Issue Editors

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Guest Editor
Department of Drug Discovery and Development, Harrison School of Pharmacy, Auburn University, Auburn, AL 36849, USA
Interests: nanoparticles; liposomes; solubility improvement; chemotherapeutic delivery
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Guest Editor
College of Pharmacy, University of Arkansas for Medical Sciences, 4301 West Markham Street, Little Rock, AR 72205, USA
Interests: drug resistance; chemotherapy failure; drug–drug interaction; anticancer drug discovery; novel mechanisms
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Cyclodextrins (CDs) are cyclic oligosaccharides composed of glucopyranose units capable of forming inclusion complexes and clathrates with a variety of hydrophobic drugs and drug carriers. The unique molecular structure and multifunctional properties of cyclodextrins can serve as drug carriers and functionalize nanomaterials for drug delivery applications.

To achieve a sustained release for soluble drugs, hydrophobic cyclodextrins can serve as suitable carriers. By forming ternary drug‒CD‒hydrophilic polymer complexes, the solubilizing and complexing properties of cyclodextrin can be significantly enhanced through the addition of small amounts of hydrophilic polymers.

This Special Issue is dedicated to exploring the pharmaceutical applications of cyclodextrins. It will cover a range of topics including drug delivery systems based on cyclodextrin-inclusion complexes, strategies to enhance drug solubility and bioavailability, formulations for controlled release, and the utilization of cyclodextrins in wound-healing materials. The focus will be on showcasing the potential of cyclodextrins in improving drug stability, targeting specific tissues, and overcoming formulation challenges.

We cordially invite researchers to submit their work to this Special Issue, with the objective of elucidating the various aspects and applications of functionalized cyclodextrins and cyclodextrin-based nanosystems. We welcome all types of articles and encourage the submission of papers and reviews.

Prof. Dr. R. Jayachandra Babu
Dr. Amit K. Tiwari
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

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Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • cyclodextrin
  • nanoparticle
  • nanocarrier
  • drug delivery system
  • gene delivery system
  • inclusion complex

Published Papers

This special issue is now open for submission.
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