Optimizing Aerosol Therapy: Strategies for Pulmonary Drug Delivery
A special issue of Pharmaceutics (ISSN 1999-4923). This special issue belongs to the section "Drug Delivery and Controlled Release".
Deadline for manuscript submissions: 28 February 2026 | Viewed by 30
Special Issue Editors
Interests: inhalation; spray drying; pulmonary drug delivery; aerosol drug delivery; nitric oxide; biopolymers; tuberculosis; nontuberculous mycobacteria
Interests: dry powder inhaler; particle engineering; inhalation therapy; high drug dose
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Aerosol therapy is a versatile approach for delivering drugs directly to the lungs of patients, offering a rapid onset of action, improving therapeutic efficacy, reducing off-target effects, and enhancing patient compliance. While particularly valuable for treating pulmonary diseases and infections, inhaled delivery can also be harnessed for systemic administration of therapeutics, including biologics and vaccines. However, whether intended for localized or systemic effects, optimizing aerosol therapy presents complex challenges, including the design of effective formulations, the advancement of inhalation devices, and the translation of laboratory findings into clinical practice.
This Special Issue of Pharmaceutics, ‘Optimizing Aerosol Therapy: Strategies for Pulmonary Drug Delivery’, aims to highlight innovative solutions and recent advances to address these challenges. We invite researchers to contribute original research articles, comprehensive reviews, and insightful perspectives on topics such as:
- Novel formulation and particle engineering strategies for inhaled drugs, biologics, and vaccines;
- Advances in inhalation devices and aerosol generation technologies;
- Analytical tools, modeling, bioequivalence, and in vitro-in vivo correlations for aerosol performance;
- Clinical, patient-centric, and regulatory considerations for inhaled therapies.
By bringing together leading experts across disciplines, this Special Issue seeks to advance our understanding of aerosol-based therapies and accelerate the development of next-generation pulmonary drug delivery systems. We warmly welcome your contributions and look forward to showcasing your latest findings and insights to help shape the future of pulmonary drug delivery.
Dr. Sara E. Maloney
Dr. Francesca Buttini
Guest Editors
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Keywords
- pulmonary drug delivery
- aerosol therapy
- inhalation drug delivery
- particle engineering
- inhaled biologics and vaccines
- aerosol characterization
- in vitro-in vivo correlation (IVIVC)
- inhaler devices
- lung deposition
- clinical translation
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