Advances in Host-Helminth Interactions
A special issue of Pathogens (ISSN 2076-0817). This special issue belongs to the section "Parasitic Pathogens".
Deadline for manuscript submissions: closed (30 June 2024) | Viewed by 1415
Special Issue Editors
Interests: pathogenesis of helminth; schistosomiasis; maternal immune activation caused by pathogens; parasites-derived molecules; hepatic disease
Interests: host-parasite interaction; the pathogenesis underlying biliary diseases
Interests: parasite developmental biology; parasite vaccine development; parasite omics; novel serological and molecular diagnostics for parasitic diseases; liver fibrosis caused by parasitic worms; translational research of helminth
Special Issue Information
Dear Colleagues,
Parasitic helminths are among the most pervasive pathogens of the animal kingdom. To complete their life cycle, these worms migrate through host tissues, causing significant damage in their wake. As a result, infection can lead to malnutrition, anemia, multi-organ damage, and increased susceptibility to co-infection. Therefore, studies of the effects of parasites from the perspective of host–helminth interactions can deepen our understanding of the pathogenesis of parasitic diseases. Meanwhile, epidemiological studies have been conducted which support the concept that helminth infections, which are characterized by the induction of strong type-2 responses or regulatory T cells, correlate with a decreased prevalence of intestinal inflammatory diseases, obesity, allergic diseases, cancer, etc. Although several helminth-derived vaccine adjuvants have been undergoing clinical trials, the identification of other new molecules, including proteins, miRNAs, lipids, glycans, as well as extracellular vesicles (EVs), derived/released from various helminths is critical for treating the various diseases from the host-pathogen interaction perspective. A better understanding of these questions is important not only from a theoretical point of view but also because of their therapeutic implications.
In this Special Issue of Pathogens, we will provide an updated representation of the current prevention, diagnosis, and pathogenesis of helminth infection. In addition, we offer further insight into future directions and emerging trends in translational science based on pathogen-derived molecules relevant to the topic.
With these aims, we invite researchers to submit high-quality works for consideration. Original research articles, narrative reviews of particular interest and case reports will be considered.
“Advances in Host-Helminth Interactions” will give specialists and scientists involved in parasitology the opportunity to share their experiences or point of view on several critical issues, with the primary objective of improving global knowledge.
Dr. Zhipeng Xu
Dr. Chao Yan
Dr. Pengfei Cai
Guest Editors
Manuscript Submission Information
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Keywords
- helminths
- host-pathogen interaction
- parasite
- immune reaction
- pathogenesis
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