Antimicrobial Resistance in Fragile and Changing Systems

A special issue of Pathogens (ISSN 2076-0817).

Deadline for manuscript submissions: 1 March 2027 | Viewed by 64

Editors


E-Mail Website
Guest Editor
Division of Infectious Diseases, University of Colorado, Anschutz Medical Campus, Aurora, CO 80045, USA
Interests: antimicrobial resistance; global burden
Special Issues, Collections and Topics in MDPI journals

E-Mail Website
Guest Editor
Department of Medicine, University of Colorado, Aurora, CO 80045, USA
Interests: antimicrobial resistance; global health; infectious disease

Special Issue Information

Dear Colleagues,

Antimicrobial resistance (AMR) remains one of the most urgent global health threats, with its burden increasingly concentrated in fragile, conflict-affected, and vulnerable settings (FCV settings), encompassing low- and middle-income countries, regions experiencing active or post-conflict instability, and populations displaced by political, climatic, or humanitarian crises. These contexts experience unique vulnerabilities, including limited, absent, or threatened diagnostics, disrupted surveillance, constrained formularies, and variable antimicrobial stewardship, all of which can accelerate the emergence and spread of resistant pathogens.

At the same time, global forces, including urbanization, environmental change, and increased human and animal mobility, are reshaping domestic and global infectious disease dynamics and facilitating cross-border transmission of resistance. These trends underscore the importance of different surveillance and control strategies to minimize the development and spread of antibiotic resistance, such as integrated One Health approaches to understand how resistance emerges, evolves, and disseminates within and beyond fragile systems.

For this Special Issue, we invite original research, comprehensive reviews, perspectives, and implementation case studies to advance our understanding of AMR in these complex environments. We welcome submissions on the following:

  • Epidemiology and determinants of AMR in fragile or rapidly changing settings;
  • Innovations in diagnostics, surveillance, and antimicrobial stewardship;
  • Impacts of conflict, displacement, and health system disruption on resistance patterns;
  • Implementation science, health system strengthening, and context-specific interventions;
  • One Health approaches linking human, animal, and environmental drivers of resistance.

Submissions addressing WHO priority pathogens or examining resistance mechanisms in resource-limited contexts are particularly encouraged. By highlighting evidence from underrepresented settings and fostering multidisciplinary collaboration, this Special Issue will inform actionable strategies and strengthen global efforts to mitigate AMR.

Dr. Andrés F. Henao-Martínez
Dr. Philip K. Angelides
Guest Editors

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-anonymized peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Pathogens is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2400 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • antimicrobial resistance
  • global health
  • fragile health systems
  • LMICs
  • conflict and displacement
  • One Health
  • antimicrobial stewardship
  • surveillance
  • diagnostics
  • implementation science
  • climate change
  • health equity

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Published Papers

This special issue is now open for submission.
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