Special Issue "Computational Analysis for Protein/Gene Structure and Interaction"
A special issue of Molecules (ISSN 1420-3049).
Deadline for manuscript submissions: closed (31 December 2019).
Interests: bioinformatics; molecular computing; machine learning; sequence alignment; systems biology
Special Issues and Collections in MDPI journals
Special Issue in International Journal of Molecular Sciences: Special Protein Molecules Computational Identification
Special Issue in Molecules: Selected Papers from the Second CCF Bioinformatics Conference (CBC 2017)
Special Issue in International Journal of Molecular Sciences: Selected Papers from 2017 Health Informatics Conference (ChongqingBioinfo2017)
Special Issue in Genes: Selected Papers from the Bioinformatics and Intelligent Information Processing Conference (BIIP2018)
Special Issue in International Journal of Molecular Sciences: Special Protein or RNA Molecules Computational Identification 2018
Special Issue in Molecules: Molecular Computing and Bioinformatics
Special Issue in International Journal of Molecular Sciences: Special Protein or RNA Molecules Computational Identification 2019
Special Issue in Cells: Biocomputing and Synthetic Biology in Cells
Special Issue in Molecules: Molecular Computing and Bioinformatics II
Protein structure analysis is a hot topic and key issue in organic chemistry and molecular biology research. Several essential protein molecules were rebuilt with Cryo-EM (cryo-electron microscopy) and their structures were published in Nature and Science. Computational structure analysis and prediction is a key process for 3D structure reconstruction. Machine learning techniques have been employed for protein secondary and tertiary structure prediction for a long time, and it seemed to have reached a bottleneck. However, the development of the Cryo-EM technique brings new challenges and requirements to computer science. Additionally, deep learning in machine learning also seems to be powerful. Therefore, there is considerable and increasing interest in developing computational methods for protein structure analysis and prediction.
Among the manuscripts in the previous Special Issue, were several outstanding works on gene structure computational analysis and prediction. This is also an important topic, and sometimes employs similar machine learning techniques. Thus, in this SI we added gene structure and interaction to the topic scope. We also welcome works on the PPI, RNA/RNA interaction, DNA/RNA binding proteins.
The Guest Editor looks forward to collecting a set of recent advances on related topics to provide a platform for researchers and bridge the gap between computer researchers and structural chemistry researchers.
Prof. Dr. Quan Zou
Manuscript Submission Information
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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Molecules is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- protein structure prediction
- protein–protein interaction network
- Cryo-EM molecule particles boxing
- Cryo-EM image process
- machine learning
- protein disorder region
- protein inter-residue contact prediction
- Computational Analysis for Protein Structure and Interaction in Molecules (39 articles)