Special Issue "Computational Analysis for Protein/Gene Structure and Interaction"
A special issue of Molecules (ISSN 1420-3049).
Deadline for manuscript submissions: 31 December 2019
Prof. Dr. Quan Zou
Institute of Fundamental and Frontier Sciences, University of Electronic Science and Technology of China, Chengdu 610054, China
Interests: bioinformatics; molecular computing; sequence alignment; systems biology
Protein structure analysis is a hot topic and key issue in organic chemistry and molecular biology research. Several essential protein molecules were rebuilt with Cryo-EM (cryo-electron microscopy) and their structures were published in Nature and Science. Computational structure analysis and prediction is a key process for 3D structure reconstruction. Machine learning techniques have been employed for protein secondary and tertiary structure prediction for a long time, and it seemed to have reached a bottleneck. However, the development of the Cryo-EM technique brings new challenges and requirements to computer science. Additionally, deep learning in machine learning also seems to be powerful. Therefore, there is considerable and increasing interest in developing computational methods for protein structure analysis and prediction.
Among the manuscripts in the previous Special Issue, were several outstanding works on gene structure computational analysis and prediction. This is also an important topic, and sometimes employs similar machine learning techniques. Thus, in this SI we added gene structure and interaction to the topic scope. We also welcome works on the PPI, RNA/RNA interaction, DNA/RNA binding proteins.
The Guest Editor looks forward to collecting a set of recent advances on related topics to provide a platform for researchers and bridge the gap between computer researchers and structural chemistry researchers.
Prof. Dr. Quan Zou
Manuscript Submission Information
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- protein structure prediction
- protein–protein interaction network
- Cryo-EM molecule particles boxing
- Cryo-EM image process
- machine learning
- protein disorder region
- protein inter-residue contact prediction
- Computational Analysis for Protein Structure and Interaction in Molecules (39 articles)