The Molecular Mechanisms Regulating Stress-Adaptive Responses in Bacteria

A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Antimicrobial Agents and Resistance".

Deadline for manuscript submissions: 15 October 2025 | Viewed by 18

Special Issue Editors


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Guest Editor
Department of General and Medical Biochemistry, Faculty of Biology, University of Gdansk, Wita Stwosza 59, 80-308 Gdańsk, Poland
Interests: bacterial physiology; biofilm; bacterial stress responses; heat shock proteins; antibiotic tolerance

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Guest Editor Assistant
Department of Medicine, Division of Gastroenterology and Hepatology, Pennsylvania State University College of Medicine, Hershey, PA, USA
Interests: biofilms; strategies to combat antimicrobial resistance; inflammatory bowel disease and tight junction

Special Issue Information

Dear Colleagues,

Bacteria combat an array of stresses in their natural setting, which elicit a variety of adaptive responses as a survival mechanism. Effective adaptive response ensues in bacterial persistence, antibiotic resistance, biofilm formation and resistance development. Understanding the intricacy of mechanisms governing the adaptation can support the advancement of suitable antimicrobials. This Special Issue brings together the cutting-edge research studies exploring the molecular mechanisms in bacterial stress adaptation, emphasizing signal transduction pathways, transcriptional and translational regulations, metabolic reprogramming, etc.

Key topics include two component regulatory systems, toxin–antitoxin systems and small regulatory RNAs in coordinating stress response. We also feature insights on bacterial persistence strategies, such as biofilm formation and virulence development and their implications on antibiotic resistance and pathogenesis. By elucidating these mechanisms, this collection aims to expand our knowledge about bacterial resilience and inform novel antimicrobial strategies.

We invite researchers to contribute to this Special Issue, which offers to impart recent discoveries in bacterial stress adaptation and promote new avenues in infectious disease research.

Dr. Ewa Laskowska
Guest Editor

Dr. Arumugam Priya
Guest Editor Assistant

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

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Keywords

  • biofilms
  • strategies to combat antimicrobial resistance
  • bacterial stress adaptation

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Published Papers

This special issue is now open for submission.
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