The Molecular Mechanisms Regulating Stress-Adaptive Responses in Bacteria

Dear Colleagues,

Bacteria combat an array of stresses in their natural setting, which elicit a variety of adaptive responses as a survival mechanism. Effective adaptive response ensues in bacterial persistence, antibiotic resistance, biofilm formation and resistance development. Understanding the intricacy of mechanisms governing the adaptation can support the advancement of suitable antimicrobials. This Special Issue brings together the cutting-edge research studies exploring the molecular mechanisms in bacterial stress adaptation, emphasizing signal transduction pathways, transcriptional and translational regulations, metabolic reprogramming, etc.

Key topics include two component regulatory systems, toxin–antitoxin systems and small regulatory RNAs in coordinating stress response. We also feature insights on bacterial persistence strategies, such as biofilm formation and virulence development and their implications on antibiotic resistance and pathogenesis. By elucidating these mechanisms, this collection aims to expand our knowledge about bacterial resilience and inform novel antimicrobial strategies.

We invite researchers to contribute to this Special Issue, which offers to impart recent discoveries in bacterial stress adaptation and promote new avenues in infectious disease research.

Dr. Ewa Laskowska
Guest Editor

Dr. Arumugam Priya
Guest Editor Assistant

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