Bacterial Extracellular Vesicles (EV): From Fundamental Studies to Innovative Applications
A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Molecular Microbiology and Immunology".
Deadline for manuscript submissions: closed (31 January 2024) | Viewed by 4567
Special Issue Editor
Interests: microbial ecology; biotechnology; growth kinetics and stoichiometry; fermentation; mathematical models of microbial growth; genome-scale metabolic reconstructions; history of microbiology
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
In eukaryotes, vesicles were early recognized as essential structures performing trafficking, neuron action, hormone release, and other functions. In contrast, microbial EVs were initially misinterpreted as waste matter. Their role then was accepted for G-negative bacteria, and only recently extended to other prokaryotes and communities (gut, soil, aquatic). Bacterial EV formation is viewed as a dynamic, self-regulated, and purposeful process integral to microbial life. One notable aspect is the innovative biotherapeutic applications of EVs as vaccines, immunoadjuvants, antibacterial agents, drug delivery, etc.
This Special Issue opens a wide gate for experimental reports, reviews, and conceptual developments on microbial EVs based on facts, not speculations. Some examples:
- Metabolic cost of vesiculation (V);
- Kinetics of V and parallel fusion;
- V strains variability;
- Competitive benefit/disadvantage of cells with enhanced V;
- EV’s role in the community.
The statement "There is nothing more practical than a good theory" suggests that a new fundamental understanding of EVs is equally valuable as innovative biotherapies.
Dr. Nicolai S. Panikov
Guest Editor
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