Immune Subversion and Pathology Associated with Bacterial Infection
A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Molecular Microbiology and Immunology".
Deadline for manuscript submissions: closed (31 August 2021) | Viewed by 5339
Special Issue Editors
Interests: blood coagulation and complement activation in response to bacterial sepsis; haemostatic properties of the vessel wall; cell biology of tissue factor pathway inhibitor.
Special Issue Information
Dear Colleagues,
We are planning a Special Issue dedicated to the subversion of host immune responses and immunopathology caused by pathogenic bacteria. We expect to publish 12–15 original articles and reviews by September 2021. Of interest are studies aimed at understanding mechanisms by which pathogenic bacteria subvert and limit the host immune response. Articles that consider pathogen-associated virulence determinants that mediate effects on the immune system are encouraged, as are effects on innate and adaptive immunity. Short- and long-term immunopathology associated with bacterial infections are of particular interest and may include mechanisms underlying intravascular coagulation, cytokine storms and other host responses that drive sepsis and organ failure. Long-term immune sequelae, including autoimmune responses are welcomed. An in-depth understanding of the effects of bacterial pathogens on the host immune system will likely help in the identification of novel targets and therapies for the treatment of infectious disease and we seek to bring relevant concepts together in a Special Issue of Microorganisms.
Dr. Florea Lupu
Prof. Mark Lang
Guest Editors
Manuscript Submission Information
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Keywords
- sepsis
- inflammation
- cytokines
- innate immunity
- adaptive immunity
- hemostatic responses to pathogens
- disseminated intravascular coagulation
- complement activation
- neutrophils
- mononuclear phagocytes
- pattern recognition receptors
- mucosal defense
- cell death in response to pathogens
- phagocytosis of pathogens
- biodefense and emerging pathogens
- microRNA host responses to infection
- intravital imaging of host responses to pathogens
