Immune Modulation to SARS-CoV-2 Vaccination and Infection (Second Edition)

A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Molecular Microbiology and Immunology".

Deadline for manuscript submissions: 28 February 2026 | Viewed by 34

Special Issue Editor


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Guest Editor
1. Laboratory of Molecular Microbiology and Biotechnology, Department of Medical Biotechnologies, University of Siena, Siena, Italy
2. Department of Medicine and Surgery, LUM University “Giuseppe Degennaro”, Bari, Casamassima, Italy
Interests: immune response to SARS-CoV-2; murine models of infection with Salmonella and Streptococcus pneumoniae; vaccination in mice; T-cell priming; mucosal vaccination; memory cells
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Special Issue Information

Dear Colleagues,

This Special Issue is the continuation of our 2022 Special Issue “Immune Modulation to SARS-CoV-2 Vaccination and Infection” (https://www.mdpi.com/journal/microorganisms/special_issues/438HD65R97).

SARS-CoV-2 infected more than 6 million people worldwide, with varying clinical outcomes. Continuous new challenges are emerging for the rapid mutations in the viral genome. Scientists are working hard to search for appropriate advanced therapies to treat COVID-19 and investigate new safe and effective vaccines capable of efficiently prevent the infection.

Until now, different vaccines have been licensed more quickly, and others are under investigation. Although the vaccination strongly reduced severe illness, and new findings and research continuously expand our knowledge about COVID-19 and SARS-CoV-2 infection, it is critical to investigate the type and the timing of immune response generated using licensed and/or new experimental vaccines, and new efficient approaches based on different delivery systems or route of vaccination.

The Special Issue “Immune Modulation to SARS-CoV-2 Vaccination and Infection (Second Edition)” aims to assemble a collection of original research articles and reviews that explore, in pre-clinical and clinical studies, the innate and adaptive immune response elicited by infection with SARS-CoV-2, or induced by different type of vaccines against SARS-CoV-2. Research works evaluating the modulation of the immune response to vaccination and/or infection, studying the type, magnitude, quality, and persistence of the immune response, are welcomed.

Dr. Fabio Fiorino
Guest Editor

Manuscript Submission Information

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Keywords

  • COVID-19
  • SARS-CoV-2
  • infection
  • immune response
  • antibody response
  • memory cells
  • vaccine
  • vaccine delivery
  • route of immunization
  • immune persistence

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Published Papers

This special issue is now open for submission.
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