Development of Nanotechnology-Directed Drug and Gene Delivery Carriers against Infectious Diseases
A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Microbial Biotechnology".
Deadline for manuscript submissions: closed (31 October 2023) | Viewed by 221
Special Issue Editors
Interests: nanotechnology; immunotherapy; brain tumor
Special Issues, Collections and Topics in MDPI journals
Interests: biomarkers; resistance; imaging; nanotechnology; long-acting therapeutics; diagnosis; liposomes; lipid nanoparticles
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The emergence of antimicrobial resistance to the existing therapies represents a major challenge towards treatment success against infectious pathogens. Overcoming resistance to the existing therapies requires a combination of drugs with different mechanisms of actions or employing newer modalities such as siRNA/CRISPR Cas9 systems both individually and in combination with a biologic or small molecule encapsulated in a nano carrier for efficient cargo delivery, reducing the therapeutic dose and off-target toxicities. Gene modalities such as mRNA, siRNA, and CRISPR are efficient drug substances that can be directed towards target cellular and tissue compartments for enhanced biodistribution profiles using nanotechnology carriers such as lipid or polymeric nanoparticles, lipopolyplex carriers, and hydrogels.
These goals will only be achieved by joining efforts from multiple disciplines including virology, geneticists, formulation scientists, clinicians, immunologists, medicinal chemists, etc.
The aim of this Special Issue is to provide an adequate multidisciplinary platform for the interchange of valuable information (both basic and applied research) that aids the development of nanoparticulate vaccines against infectious diseases, RNA/CRISPR delivery, and biologics and/ small molecule inhibitors targeted towards reversing antimicrobial resistance to the existing therapies.
As a Guest Editor of the Special Issue, I invite you to submit research articles, review articles, and short communications related to gene and or CRISPR delivery, lipid and polymeric nanoparticulate vaccines and systems loading biologics/small molecule inhibitors targeted towards reversing microbial resistance to the existing therapies.
Dr. Héctor R. Méndez-Gómez
Dr. Dhruvkumar M. Soni
Guest Editors
Manuscript Submission Information
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Keywords
- resistance
- nanotechnology
- gene delivery
- vaccines
- infectious
- anti-microbial
- lipid nanoparticles
- biologics
- small molecule inhibitors
- polymeric nanoparticles
- CRISPR
- elimination
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