Research on Fungal Infections and Antimicrobial Resistance
A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Medical Microbiology".
Deadline for manuscript submissions: 31 August 2025 | Viewed by 108
Special Issue Editor
Interests: medical mycology; fungal infections; drug-resistance
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The incidence of fungal infections is predominately rising, particularly among high-risk populations such as cancer patients, individuals with neutropenia, HIV-positive individuals, organ transplant recipients, and those undergoing immunosuppressive therapy. This increase is further exacerbated by the emergence of drug-resistant and multidrug-resistant fungal strains, resulting in invasive fungal infections. Disseminated fungal diseases, such as Aspergillosis and Candidemia, are life-threatening infections with high mortality and morbidity rates in immunosuppressed patients. As a result, early diagnosis and prompt initiation of appropriate treatment are critical for effective disease management.
In 2023, the World Health Organization (WHO) published a list of fungal priority pathogens, categorizing several fungal species as high-priority or critical-priority pathogens. Research focusing on this list has become a global concern, as some of these pathogens exhibit drug resistance, leading to therapeutic failure and poor clinical outcomes. Addressing this issue necessitates an in-depth understanding of resistance mechanisms, including novel pathways contributing to resistance. Whole-genome sequencing has proven to be a powerful tool for identifying genes associated with drug resistance, providing valuable insights for developing targeted treatment strategies.
Over recent decades, the use of immunomodulators to enhance the host immune response against fungal infections has garnered significant attention from researchers. Additionally, the One Health approach to combating resistant fungal infections emphasizes the need for innovative therapeutic strategies to overcome resistance mechanisms and improve patient outcomes.
This Special Issue welcomes original research articles, review articles, perspectives, and short communications on these critical topics.
Dr. Maryam Roudbary
Guest Editor
Manuscript Submission Information
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Keywords
- fungal infections
- drug-resistance
- mechanism of resistance
- fungi–host interaction
- immunomodulators
- whole-genome sequencing
- novel antifungals
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