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Microorganisms
Special Issues
Gut Microbiome Composition in Livestock and Mice
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Gut Microbiome Composition in Livestock and Mice

A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Veterinary Microbiology".

Deadline for manuscript submissions: 30 November 2025 | Viewed by 437

Special Issue Editors

Prof. Dr. Peng Huang

E-Mail Website
Guest Editor
College of Veterinary, Hunan Agricultural University, Changsha 410128, China
Interests: gut microbiota; veterinary traditional Chinese medicine (TCM); plant extracts; animal gut health; natural feed additives
Dr. Qian Lin

E-Mail Website
Guest Editor
Institute of Bast Fiber Crops, Chinese Academy of Agricultural Sciences, Changsha 410205, China
Interests: gut microbiota; veterinary traditional Chinese medicine (TCM); plant extracts; animal gut health; natural feed additives; animal nutrition

Special Issue Information

Dear Colleagues,

The Special Issue entitled “Gut Microbiome Composition in Livestock and Mice” aims to present recent research on any aspects of the gut microbiome in livestock (pigs, chickens, cows, sheep) and mice. Understanding the gut microbiome’s natural composition and the factors that shape it is critical to advancing animal health and improving production efficiency. This topic is of great significance as it addresses not only the natural variations in microbiome composition but also the impacts of external interventions, such as feed additives and veterinary treatments, which are essential for developing sustainable agricultural practices and improving livestock health.

Some of its focal points include, but are not limited to, the following:

  • Natural variations in the gut microbiome composition of livestock and mice in the absence of external interventions.
  • The effects of feed additives, veterinary drugs, and plant extracts on the gut microbiome and their implications for animal health.
  • Comparative studies on the gut microbiome of different species, including pigs, chickens, cows, sheep, and mice.
  • The relationship between gut microbiome composition and overall livestock performance, health, and immunity.

Reviews, original research, and communications will be welcome.

Prof. Dr. Peng Huang
Dr. Qian Lin
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Microorganisms is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • gut
  • microbiome
  • livestock
  • mice
  • health

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Further information on MDPI's Special Issue policies can be found here.

Published Papers (1 paper)

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19 pages, 793 KiB  
Review
Advances in Donkey Disease Surveillance and Microbiome Characterization in China
by Muhammad Zahoor Khan, Yan Li, Mingxia Zhu, Mengmeng Li, Tongtong Wang, Zhenwei Zhang, Wenqiang Liu, Qingshan Ma and Changfa Wang
Microorganisms 2025, 13(4), 749; https://doi.org/10.3390/microorganisms13040749 - 26 Mar 2025
Viewed by 340
Abstract
This review article highlights the surveillance of bacterial, viral, and parasitic diseases in donkey populations in China. Key findings highlight significant threats from Equine herpesviruses (EHV-8 and EHV-1), which cause encephalitis, abortion, and respiratory distress. Several parasitic infections including Giardia duodenalis, Cryptosporidium [...] Read more.
This review article highlights the surveillance of bacterial, viral, and parasitic diseases in donkey populations in China. Key findings highlight significant threats from Equine herpesviruses (EHV-8 and EHV-1), which cause encephalitis, abortion, and respiratory distress. Several parasitic infections including Giardia duodenalis, Cryptosporidium spp., Enterocytozoon bieneusi, and Toxoplasma gondii present important zoonotic concerns across multiple regions of China. Additionally, this review synthesizes current knowledge on donkey microbiota across various body sites and examines their functional significance in health and disease. The complex relationship between the microbiota and host health represents a critical area of research in donkeys. Recent molecular advancements have enhanced our understanding of the diverse microbial ecosystems inhabiting different body sites in donkeys and their profound impact on health outcomes. As single-stomach herbivores, donkeys possess complex microbial communities throughout their digestive tracts that are essential for intestinal homeostasis and nutritional processing. Significant variations in microbiota composition exist across different intestinal segments, with the hindgut displaying greater richness and diversity compared to the foregut. Beyond the digestive system, distinct microbial profiles have been characterized across various body sites including the skin, oral cavity, reproductive tract, and body secretions such as milk. The health implications of donkey microbiota extend to critical areas including nutrition, immune function, and disease susceptibility. Research demonstrates how dietary interventions, environmental stressors, and physiological states significantly alter microbial communities, correlating with changes in inflammatory markers, antioxidant responses, and metabolic functions. Additionally, specific microbial signatures associated with conditions like endometritis and respiratory disease suggest the potential for microbiota-based diagnostics and therapeutics. The identification of antibiotic-resistant strains of Proteus mirabilis and Klebsiella pneumoniae in donkey meat highlights food safety concerns requiring enhanced monitoring systems and standardized safety protocols. These findings provide a foundation for improved donkey healthcare management, including targeted disease surveillance, microbiota-based interventions, and protective measures for those working with donkeys or consuming donkey-derived products. Full article
(This article belongs to the Special Issue Gut Microbiome Composition in Livestock and Mice)
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