Trichomonas vaginalis and Trichomoniasis: Biomarkers and Possible Pharmacological Alternatives

A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Medical Microbiology".

Deadline for manuscript submissions: 31 December 2025 | Viewed by 242

Special Issue Editors


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Guest Editor
Laboratorio de Patogénesis Celular y Molecular Humana y Veterinaria, Posgrado en Ciencias Genómicas, Universidad Autónoma de la Ciudad de México (UACM), San Lorenzo 290, Col. Del Valle, Mexico City 03100, Mexico
Interests: trichomoniasis and the pharmacological alternatives for resistant trichomoniasis; analysis of genomics and proteomics of this parasite through the search of the possible biomarkers for the diagnosis and treatment of this parasite

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Co-Guest Editor
Facultad de Química, Universidad Autónoma de Yucatán, Calle 43 No. 613 x Calle 90, Col. Inalámbrica, Mérida 97069, Yucatán, Mexico
Interests: trichomoniasis and the immunological response in the host during the infection

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Co-Guest Editor
Center for Research and Advanced Studies of the National Polytechnic Institute, Universidad Autonoma de la Ciudad de Mexico, Ciudad de Mexico, Mexico
Interests: epigenomics of Trichomonas vaginalis and its correlation with other infections of the urogenital tract in humans

Special Issue Information

Dear Colleagues,

The sexually transmitted infection caused by Trichomonas vaginalis, known as trichomoniasis, affects more than 370 million people worldwide. The virulence mechanisms of this parasite in the presence of cations in the urogenital tract, as well as its resistance to the drug treatments of choice, allow this microorganism to survive in the human urogenital tract. This infection can cause vaginitis, cervicitis, abortion and preterm birth in females and urethritis, prostatitis or infertility in males. Some recent studies indicate that T. vaginalis infection is a risk factor of prostate and cervicouterinal cancers through a persistent inflammatory reaction of epithelial cells. The mechanism of regulation of the genetic expression and the immunological response of this parasite in the host might be useful for the search for biomarkers for the diagnosis and treatment of this infection. The detection of molecules relevant to this infection during resistant trichomoniasis is highly important and detection methods include biomarkers of treatment and diagnosis of trichomoniasis. The aim of this Special Issue of Microorganisms is to present a collection of articles addressing topics with the most relevant research about the diagnosis and treatment of this infection, as well as the description of key molecules that can serve as biomarkers.

Dr. María Elizbeth Alvarez-Sánchez
Dr. Julio César Torres-Romero
Dr. Elisa Elvira Figueroa-Angulo
Guest Editors

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Keywords

  • trichomoniasis in men
  • biomarkers
  • pharmaceutical alternatives

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Published Papers

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