Common Clinical Viral Pathogens: Detection and Treatment

A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Virology".

Deadline for manuscript submissions: closed (15 December 2024) | Viewed by 3659

Special Issue Editor


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Guest Editor
Laboratory for Molecular Virology and Bacteriology, Department of Molecular Medicine, Ruđer Bošković Institute, 10000 Zagreb, Croatia
Interests: viral metagenomics; virus; diversity; zoonoses; HPV

Special Issue Information

Dear Colleagues,

This Special Issue, "Common Clinical Viral Pathogens: Detection and Treatment," will be focused on research exploring the identification and study of, and treatment strategies for commonly encountered clinical viral pathogens in both human and animal populations. For example, research on rabies, mpox, HPV, HIV and SARS-CoV-2 will be included.

We invite submissions of original research and reviews that investigate areas such as molecular diagnostic methods, serology, genomic studies, the development of vaccines, immune markers, and antiviral treatments. Research on zoonotic viral pathogens, which can impact both human health and animal health, is particularly welcomed.

The goal of this Special Issue is to offer a broad view of how research on viral pathogens can help improve outcomes for patients, guide public health policies, and inform future research directions. We hope this collection of studies will be thought-provoking, encourage collaboration, and advance our understanding of these important infectious diseases.

Dr. Ivana Šimić
Guest Editor

Manuscript Submission Information

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Keywords

  • virus
  • zoonoses
  • vaccine
  • molecular methods
  • serology

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Published Papers (1 paper)

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Research

15 pages, 1759 KiB  
Article
A Multiplex Polymerase Chain Reaction Assay for the Detection of Herpes Simplex Virus, Cytomegalovirus, and Varicella-Zoster Virus in Cerebrospinal Fluid
by Tatjana Luzius, Samuel D. Jeske, Julia Baer, Uta Goelnitz, Ulrike Protzer and Jochen M. Wettengel
Microorganisms 2025, 13(1), 111; https://doi.org/10.3390/microorganisms13010111 - 8 Jan 2025
Viewed by 1096
Abstract
Viral meningitis poses a significant clinical challenge due to its rapid onset and potential progression to life-threatening encephalitis. Early detection of treatable viral pathogens such as Herpes simplex virus (HSV), Cytomegalovirus (CMV), and Varicella-zoster virus (VZV) is essential for initiating appropriate therapies. However, [...] Read more.
Viral meningitis poses a significant clinical challenge due to its rapid onset and potential progression to life-threatening encephalitis. Early detection of treatable viral pathogens such as Herpes simplex virus (HSV), Cytomegalovirus (CMV), and Varicella-zoster virus (VZV) is essential for initiating appropriate therapies. However, multiplex PCRs for the rapid and simultaneous detection of these pathogens are scarce due to the complex PCR design and the elaborate validation process using cerebrospinal fluid samples. In this study, we established and validated a novel multiplex PCR assay for detecting HSV, CMV, and VZV in cerebrospinal fluid samples and implemented the assay on a fully automated platform. Full article
(This article belongs to the Special Issue Common Clinical Viral Pathogens: Detection and Treatment)
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