Emerging and Re-emerging Domestic Animal Parasites: Implications for One Health

A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Parasitology".

Deadline for manuscript submissions: closed (31 August 2023) | Viewed by 2227

Special Issue Editor

Institute of Traditional Chinese Veterinary Medicine, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, China
Interests: molecular characteristics of domestic animal parasites
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Emerging and re-emerging parasitic infections in domestic animals pose significant global challenges for animal and human health. Molecular techniques have revolutionized our understanding of these parasites, providing valuable insights into their genetic diversity, epidemiology, and pathogenesis. The proposed Special Issue will focus on using molecular approaches to better understand these parasites and develop effective control strategies. One major advantage of molecular techniques is their ability to rapidly identify and characterize new or previously unknown pathogens. For example, PCR-based assays have been developed for detecting and identifying various parasitic infections, including those caused by protozoa, helminths, and arthropods. Next-generation sequencing technologies have also allowed for high-throughput sequencing of parasite genomes, enabling researchers to investigate genetic diversity and identify novel targets for drug and vaccine development.

In addition to identifying new pathogens, molecular techniques can provide valuable insights into parasite evolution and transmission dynamics. For instance, microsatellite markers and SNP analysis can reveal patterns of genetic variation within and among parasite populations, which can inform our understanding of parasite dispersal and transmission. Similarly, the genetic characterization of parasite populations can help identify infection sources and track the spread of disease outbreaks.

Similarly, using molecular approaches in vaccine and drug development can lead to more targeted and effective treatments for parasitic infections. Overall, the proposed Special Issue will be an important forum for researchers to share their latest findings and insights into the biology and control of domestic animal parasites and prevent the spread of parasitic infections, ultimately benefiting both animal and human health.

Dr. Kun Li
Guest Editor

Manuscript Submission Information

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Keywords

  • host–parasite interactions
  • microbiome
  • One Health
  • pathogenesis

Published Papers (1 paper)

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Review

18 pages, 2327 KiB  
Review
Recent Progress in the Detection of Surra, a Neglected Disease Caused by Trypanosoma evansi with a One Health Impact in Large Parts of the Tropic and Sub-Tropic World
by Jeongmin Kim, Andrés Álvarez-Rodríguez, Zeng Li, Magdalena Radwanska and Stefan Magez
Microorganisms 2024, 12(1), 44; https://doi.org/10.3390/microorganisms12010044 - 26 Dec 2023
Cited by 1 | Viewed by 1925
Abstract
Surra is a wasting disease triggered by infection with Trypanosoma evansi, a protozoan blood parasite that causes mortality and morbidity in a broad spectrum of wild and domestic animals and occasionally humans. Trypanosoma evansi has the widest geographical spread among all pathogenic [...] Read more.
Surra is a wasting disease triggered by infection with Trypanosoma evansi, a protozoan blood parasite that causes mortality and morbidity in a broad spectrum of wild and domestic animals and occasionally humans. Trypanosoma evansi has the widest geographical spread among all pathogenic trypanosomes, inflicting significant worldwide economic problems due to its adverse effects on meat and milk production. For diagnosis, most endemic countries continue to rely on traditional parasitological and serological techniques, such as the analysis of blood smears by microscopy and the Card Agglutination Test for T. evansi (CATT/T. evansi). Although these techniques suffer from a limited positive predictive value (PPV), resource constraints in endemic countries often hinder the adoption of more advanced diagnostic tools such as PCR. This paper addresses diverse diagnostic approaches for identifying T. evansi and assesses their viability in field settings. Moreover, it underscores the urgency of transitioning towards molecular diagnostic techniques such as Loop-Mediated Isothermal Amplification (LAMP) and Recombinase Polymerase Amplification (RPA) for dependable high-PPV point-of-care (POC) diagnostics. Finally, this review delves into strategies to enhance and refine next-generation diagnostics for Surra as part of a One Health approach. Full article
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