Probiotics and Gut Microbiome Dynamics in Health and Disease
A special issue of Microorganisms (ISSN 2076-2607). This special issue belongs to the section "Gut Microbiota".
Deadline for manuscript submissions: 31 May 2026 | Viewed by 11
Special Issue Editors
2. Department of Molecular Biology & Genetics, Democritus University of Thrace, 68100 Alexandroupolis, Greece
Interests: food microbiology; applied & molecular microbiology; functional foods; high-added-value products
Special Issues, Collections and Topics in MDPI journals
Interests: bioinformatics; microbiome research; biomarker discovery; translational medicine
Interests: cancer; aldehyde dehydrogenases; cancer stem cells; DNA damage; oxidative stress; chemoresistance; natural products; antioxidants
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The Special Issue “Probiotics and Gut Microbiome Dynamics in Health and Disease” aims to explore and highlight how gut microbial communities influence host physiology, development, and overall well-being across biological systems. Gut microbiota play key roles in metabolic regulation, immunity, behavior, and resilience to environmental stressors. Microbial transmission patterns, early-life colonization, dietary habits, and lifestyle factors strongly shape microbial diversity and functional capacity. Growing research and public interest in probiotics, synbiotics, postbiotics, and functional foods, including innovative plant-based and fermented formulations, underscore their potential to beneficially modulate gut ecosystems in both health and disease contexts. Mechanistic insights increasingly reveal how microbial metabolites, community interactions, and strain-specific functions affect host outcomes. Computational advances in microbiome research enable the discovery of biomarkers and novel probiotic candidates. This Special Issue welcomes contributions that expand the molecular, functional, nutritional, translational, and computational understanding of gut microbiota and their role in maintaining or restoring health across diverse biological systems.
This Special Issue entitled "Probiotics and Gut Microbiome Dynamics in Health and Disease" aims to present recent research on any aspect of the gut microbiome. Some of its focal points include, but are not limited to, the following:
- Microbial community dynamics, host–microbe interactions, and microbiome-derived metabolites;
- Probiotics, prebiotics, synbiotics, postbiotics, and functional foods targeting disease prevention and health promotion;
- Bioinformatics, multi-omics analysis, genome sequencing, and computational tools for studying microbiome function and probiotic potential;
- Microbiome-based biomarkers and personalized interventions in precision medicine;
- Effects of diet, genes, lifestyle, and environmental factors on microbiota composition and function.
Reviews, original research, and communications will be welcome.
Dr. Anastasios Nikolaou
Guest Editor
Dr. Margaritis Tsifintaris
Dr. Ilias Tsochantaridis
Guest Editor Assistants
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Microorganisms is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- gut microbiota
- probiotics
- functional foods
- fermented foods
- maternal–infant microbiome
- diet–microbiome interactions
- microbial colonization
- microbial metabolites
- microbiome biomarker
- dysbiosis
- precision nutrition
- host–microbe interactions
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