Special Issue "Metabolite Markers of Phytochemicals"

A special issue of Metabolites (ISSN 2218-1989).

Deadline for manuscript submissions: 20 December 2018

Special Issue Editor

Guest Editor
A/Prof. Chi Chen

Department of Food Science and Nutrition, University of Minnesota, St. Paul, MN 55108, USA
Website | E-Mail
Interests: metabolomics; nutrient metabolism; xenobiotic metabolism; nutritional biochemistry; animal nutrition; pharmacometabolomics; lipidomics; microbial metabolism

Special Issue Information

Dear Colleagues,

Phytochemicals are important natural components of human diet and animal feed. Bioactive phytochemicals are commonly used as dietary supplements, food and feed additives, and even as pharmacological agents. Benefits and adverse effects of bioactive phytochemicals are closely associated with the bidirectional interactions between phytochemicals and the metabolic system, such as the disposition of phytochemicals, the regulation of nutrient, antioxidant, and microbial metabolism, and overdose-induced toxicities. Therefore, any metabolites that respond sensitively to phytochemical exposure and treatments are potential metabolite markers of phytochemicals, such as the biotransformation products of phytochemicals and the members of a specific metabolic pathway. This Special Issue aims to examine these metabolite markers of phytochemicals as well as underlying mechanisms, the significances, and the applications of these metabolite markers. The coverage of this Special Issue includes, but is not limited to, the following topics:

  • Exposure markers and metabolic routes of phytochemicals
  • Metabolic effects on phytochemicals on the digestion, absorption, distribution and metabolism of nutrients and antioxidants
  • Influences of phytochemicals on microflora and microbial metabolism
  • Metabolites associated with the toxicity of phytochemicals
  • Metabolic interactions between phytochemicals and pharmacological agents
Dr. Chi Chen
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Metabolites is an international peer-reviewed open access quarterly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 850 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • metabolite markers
  • metabolomics
  • phytochemical
  • nutrient metabolism
  • microbial metabolism
  • xenobiotic metabolism

Published Papers

This special issue is now open for submission.
Back to Top