New Insights on the Role of Lipid Metabolism in the Development of Cardiac Dysfunction

A special issue of Metabolites (ISSN 2218-1989). This special issue belongs to the section "Lipid Metabolism".

Deadline for manuscript submissions: 1 August 2024 | Viewed by 242

Special Issue Editor


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Guest Editor
Heart and Muscle Metabolism Laboratory, Department of Health and Exercise Physiology, Ursinus College, Collegeville, PA 19426, USA
Interests: lipid metabolism; exercise adaptations; cardiac physiology
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Special Issue Information

Dear Colleagues,

Myocardial lipid metabolism remains of critical importance in the resynthesis of ATP and maintenance of contraction in the healthy heart. However, lipid metabolism is suggested as a culprit mechanism in the development of cardiac dysfunction in a variety of chronic diseases such as pressure-overload hypertrophy, diabetes, obesity, and heart failure. Excessive fatty acid oxidation, decreased fatty acid oxidation, “lipotoxicity”, and changes in other lipid metabolic pathways have been implicated as potential causes of cardiac dysfunction. However, the distinguishing metabolic aberrancy in lipid metabolism could be distinct to specific pathologies or populations.     

This Special Issue of Metabolites will be dedicated to publishing original articles and reviews that provide insight into the role of alterations in myocardial lipid metabolism that contribute to the development of cardiac dysfunction. We welcome the submission of original studies or review articles that highlight changes in lipid metabolism that are the cause or consequence of cardiac dysfunction in specific pathologies. In addition, studies and papers seeking to identify changes in lipid metabolism that contribute to differences in sex, race/ethnicity, and aging will be of particular interest.   

Dr. Stephen C. Kolwicz
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Metabolites is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Published Papers

This special issue is now open for submission.
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