Special Issue "Metabolic Strategies in Hypoxia"
A special issue of Metabolites (ISSN 2218-1989).
Deadline for manuscript submissions: closed (30 June 2021).
Interests: hypoxia; ischemia; comparative neurophysiology; metabolism; thermoregulation
Interests: metabolic rate depression; anoxia tolerance; enzyme regulation; microRNA; epigenetics; freeze tolerance; estivation; hibernation
Hypoxia-tolerant organisms are adapted to thrive in challenging low-oxygen environments. These species commonly employ a combination of metabolic strategies to achieve this feat, including metabolic rate suppression, targeted switching of metabolic fuel substrate use, mobilization of metabolites, and/or elegant adaptations that either buffer or permit the accumulation of otherwise deleterious metabolic end products. This suite of metabolic adaptations is critical to both short- and long-term survival in hypoxic environments, and this Special Issue of Metabolites, entitled “Metabolic Strategies in Hypoxia”, will explore recent advances in our understanding of adaptive metabolic strategies, and of the underlying signaling pathways that mediate and coordinate these responses. Specific areas of interest include but are not limited to mechanisms underlying metabolic rate suppression, fuel switching, or other metabolic adaptations to hypoxia, regulation, and integration of these responses within the peripheral and central nervous systems, and in a systemic context, and exploration of the evolutionary origins of mechanisms of hypoxia tolerance.
Dr. Matthew Pamenter
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Metabolites is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 1800 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Metabolic rate suppression
- Alternative end products
- Alternative metabolic substrates
- Energetic trade-offs (e.g., thermogenesis vs. metabolic rate suppression)
- Oxygen conformer
- Comparative physiology