Chromatographic Methods in Metabolomics

Dear Colleagues,

Analytical approaches based on liquid or gas chromatography coupled to mass spectrometry have become a powerful tool for the measurement and quantification of specific classes or groups of metabolites. Metabolite identification presents important pitfalls, but better chromatographic separation provides increased confidence in the annotation, which is critical for data interpretation. The versatility of LC/GC–MS couplings due to different combinations of various chromatographic and mass spectrometric acquisition methods has resulted in the advent of diverse workflows, making the coverage of different groups of metabolites possible. This Special Issue of Metabolites, “Chromatographic Methods in Metabolomics”, will be dedicated to the different workflows based on LC or GC coupled to mass spectrometry, including data mining and handling procedures. Objects could be humans, animals, cell cultures, and bacteria, among others. The topics that will be covered by this Special Issue include, but are not limited to: Biofluids and tissue metabolomics, including sample preparation for chromatographic analysis, targeted and untargeted LC/GC–MS analysis and their applications, complementary methodologies to investigate gut microbiota and the relationship with the metabolome, quality assurance, metabolic flux analysis based on LC/GC–MS analysis, and challenges in metabolite annotation by LC or GC mass spectrometry. Manuscripts dealing with other suitable challenging issues are also encouraged.

Prof. Tamara García Barrera
Prof. José Luis Gómez Ariza
Dr. Ana Arias Borrego
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Metabolites is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• Liquid chromatography mass spectrometry
• Gas chromatography mass spectrometry
• Sample preparation
• Metabolite annotation