Obesity and Metabolic Syndrome in Children: Insights, Interventions and Emerging Perspectives, 2nd Edition
A special issue of Metabolites (ISSN 2218-1989). This special issue belongs to the section "Endocrinology and Clinical Metabolic Research".
Deadline for manuscript submissions: 31 October 2025 | Viewed by 39
Special Issue Editors
Interests: nutritional and metabolic diseases in childhood; obesity; metabolic syndrome; insulin resistance; clinical endocrinology; oxidative stress; selenium
Special Issues, Collections and Topics in MDPI journals
2. School of Medicine, University of Belgrade, 11 000 Belgrade, Serbia
Interests: metabolic consequences of childhood obesity; metabolically healthy obesity; endocrine consequences of childhood obesity; metabolic syndrome in children; type 1 and type 2 diabetes in children; puberty; DSD; adrenals
Special Issue Information
Dear Colleagues,
This second edition of the Special Issue "Obesity and Metabolic Syndrome in Children: Insights, Interventions and Emerging Perspectives" came as a natural consequence of the success of the first edition, and it is also a continuation of the first one.
Metabolic syndrome in children represents a nuanced continuum intricately woven by various contributing factors, beginning with fetal programming. The prenatal environment plays a pivotal role in shaping metabolic trajectories, impacting organ development and programming metabolic pathways. Genetic predispositions add an additional layer of complexity, influencing susceptibility to metabolic dysregulation. The interplay between specific gene variants may contribute to altered lipid metabolism, insulin resistance, and other hallmarks of metabolic syndrome. Oxidative stress, which is characterized by an imbalance between reactive oxygen species and antioxidant defenses, has emerged as a key mechanistic link. Increased oxidative stress can disrupt cellular function and contribute to the development of insulin resistance and inflammation. Moreover, environmental risk factors, encompassing lifestyle, dietary habits, and pollutant exposure, further modulate the trajectory of metabolic health in children. Investigating these intricate relationships provides a comprehensive understanding of the origins and progression of metabolic syndrome in pediatric populations, offering valuable insights for targeted interventions and early-life prevention strategies.
Dr. Teofana Otilia Bizerea-Moga
Dr. Rade Vukovic
Guest Editors
Manuscript Submission Information
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Keywords
- metabolic syndrome in children
- childhood obesity
- hypertension
- glucose tolerance
- insulin resistance
- nutritional status
- metabolomics
- oxidative stress
- trace elements—selenium
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