Psychosis Mechanisms and Interventions
A special issue of Medicina (ISSN 1648-9144). This special issue belongs to the section "Psychiatry".
Deadline for manuscript submissions: 30 April 2026 | Viewed by 17
Special Issue Editors
Interests: psychosis; neurobiology; early intervention; cognitive dysfunction; trauma; dopamine; sleep disturbances; antipsychotics; digital psychiatry; precision medicine
2. Department of Biomedical and Neuromotor Sciences, University of Bologna, 40126 Bologna, Italy
Interests: mental illness; clinical assessment; clinical psychiatry; sleep disorders
Special Issue Information
Dear Colleagues,
Psychosis encompasses a diverse spectrum of symptoms—such as hallucinations, delusions, and thought disorganization—that can manifest across a range of psychiatric and neurological disorders. Despite significant advances in diagnosis and treatment, the pathophysiological mechanisms underlying psychosis remain only partially understood, and existing interventions often fail to fully address the complexity and heterogeneity of these syndromes. Recent years have seen a surge in translational and interdisciplinary research, integrating neurobiology, genetics, cognitive neuroscience, pharmacology, and psychosocial models to offer a more nuanced understanding of psychosis.
This Special Issue of Medicina aims to gather innovative contributions that explore the mechanisms, risk factors, and interventions associated with psychotic disorders. We welcome original research articles, systematic reviews, meta-analyses, and theoretical perspectives that address neurodevelopmental pathways, neurochemical dysregulation (e.g., dopaminergic, glutamatergic, or immune-mediated), trauma-related vulnerabilities, circadian and sleep-related alterations, and social determinants of psychosis. We particularly welcome submissions that focus on early identification, preventive strategies, novel pharmacological and non-pharmacological treatments (e.g., digital tools, psychotherapy, lifestyle interventions), and the role of precision psychiatry in personalizing care.
By compiling multidisciplinary insights, this Special Issue aims to foster a comprehensive framework that enhances our understanding, prediction, and treatment of psychosis across the lifespan.
Dr. Giorgia Varallo
Guest Editor
Dr. Valentina Baldini
Guest Editor Assistant
Manuscript Submission Information
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Keywords
- psychosis
- neurobiology
- early intervention
- cognitive dysfunction
- trauma
- dopamine
- sleep disturbances
- antipsychotics
- digital psychiatry
- precision medicine
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