Special Issue "Advanced Materials in Cardiovascular Nanomedicine"
A special issue of Materials (ISSN 1996-1944).
Deadline for manuscript submissions: 31 May 2020.
Interests: blood platelets; nanoparticle-cell; nanoparticle-platelet interactions; nanotoxicology; cancer; pharmacology; nanomedicine
Interests: pharmacological treatments; gastrointestinal diseases; platelet-tumour cell; nanomedicine
Cardiovascular disease is one of the leading health-related problems worldwide and, according to the World Health Organization (WHO), constitutes the major cause of death in the first world. It includes disorders in which the dysfunction of the heart (congenital or secondary to rheumatic heart disease, for example) or the build-up of atheroma plaques in the arteries lead to coronary heart disease, cerebrovascular disease, and peripheral arterial disease.
Both early diagnoses and novel treatments for these diseases are under continuous development. In fact, research involving the design of new blood-compatible materials used during surgical procedures and the application of nanotechnology for the diagnosis and treatment of cardiovascular diseases has gained increasing interest during the past few years.
The development of atherosclerosis in blood vessels can lead to thrombosis and lack of blood supply to the dependent tissues and, therefore, to the development of symptoms and complications (angina, myocardial infarction, stroke, or peripheral thrombosis) that are usually pharmacologically treated with different groups of drugs. However, cardiothoracic surgery involving angioplasty, the insertion of stents, or coronary artery bypass are often also needed. In the case of cardiovascular diseases secondary to birth defects or dysfunction of heart valves, surgery involving the use of different types of material for the repair of the congenital defects or the replacement of heart valves by mechanical or bio-prosthetic valves can be also necessary. During cardiothoracic surgery, the use of extracorporeal circulation, whereby blood is circulated outside the body through synthetic surfaces within a perfusion circuit, is required. Thrombosis can occur when the blood contacts foreign surfaces as a result of the activation of the coagulation cascade and of platelets. Therefore, patients should be treated with anticoagulants during the surgical procedure and sometimes for the rest of their lives if a prosthetic valve, for example, is implanted, thus increasing their risk of bleeding.
This Special Issue is focused on the potential applications of new materials or nanomaterial platforms for the diagnosis or treatment of cardiovascular diseases or in situations where the development of blood-compatible surfaces for medical applications is critical. Full papers, communications, and reviews covering one or several of the topics indicated by (or related to) the keywords below are welcome.
Prof. Dr. Maria Santos-Martinez
Prof. Dr. Carlos Medina Martin
Prof. Dr. Marek Radomski
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Materials is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Diagnosis of cardiovascular diseases
- Treatment of cardiovascular diseases
- Blood compatibility of materials or nanomaterials
- Drug delivery