Special Issue "Marine Natural Products against Brain Diseases and Injuries"
A special issue of Marine Drugs (ISSN 1660-3397).
Deadline for manuscript submissions: 31 December 2020.
Interests: neuroprotective agents from marine and terrestrial resources; molecular and cellular neurobiology; molecular neuropharmacology of neurodegenerative diseases
Interests: bioactive natural products with neuroprotective potentials; molecular neuropharmacology; system pharmacology; functional foods; computational biology
Bioactive natural products are promising for the development of novel therapeutic agents. Although terrestrial sources have always had priority over marine sources, the latter have recently received equal attention because of their highly diverse bioactive molecules with unique chemical structure and bioactivity. Marine lives, such as microoganisms, algae, fungi, sponge, cnidarins, molluscs, etc., are abundant in diverse molecules that are primarily synthesized to cope with various environmental stimuli. However, these bioactive compounds have shown numerous medicinal activities, including neuroprotective, antioxidant, anti-inflammatory, immunomodulatory, and anti-proliferative properties. With the growing prevalence of oxidative stress- and inflammation-mediated chronic brain dieseases, including Alzheimer’s, Parkinson’s, and Huntington’s diseases, natural product researchers and drug designers have been focusing their attention on the discovery and development of novel therapeutic leads from marine natural products or their skeleton. Many of these compounds modulate various molecular targets of brain-specific biochemical and signaling pathways, suggesting their therapeutic significance in the management of neurodegenerative disorders, brain injuries and tumors.
This Special Issue will cover the isolation and characterization of novel compounds from marine organisms, the bioactivity of already known molecules, structure–activity relationship, and the mechanism of neuroprotection against various toxic insults representing in vitro and in vivo models of neurodegeneration, brain injury, and tumors. Both original research and review papers are welcome.
Prof. Dr. II Soo Moon
Prof. Dr. Abdul Hannan
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All papers will be peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Marine Drugs is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2000 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
- Marine organisms
- Bioactive natural products
- Structure–activity relationships
- Pharmacological mechanism of action
- Neurodegenrative disorders, ischemic stroke, and acute brain injury
- Brain tumors