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Marine Drugs
Special Issues
Selected Papers from BIOPROSP_19
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Selected Papers from BIOPROSP_19

A special issue of Marine Drugs (ISSN 1660-3397).

Deadline for manuscript submissions: closed (31 December 2019) | Viewed by 4225

Special Issue Editors

Prof. Dr. Espen Hansen

E-Mail Website
Guest Editor
Marbio, UiT The Arctic University of Norway, Breivika, N-9037 Tromsø, Norway
Interests: bioactive natural products; mass spectrometry; chromatography; metabolomics; bioactivity screening
Special Issues, Collections and Topics in MDPI journals
Dr. Teppo Rämä

E-Mail Website
Co-Guest Editor
Marbio, UiT The Arctic University of Norway, Breivika, N-9037 Tromsø, Norway
Interests: marine fungi; culturing; metagenomics; microbial diversity; new antimicrobials; bioactivity

Special Issue Information

Dear Colleagues,

BIOPROSP_19: Unlocking the Potential of Biomolecules from Marine Environments

The importance of marine resources for biotechnology is increasing. Marine resources are sourced for biomass to be used in different fields of industry, novel enzymes, and bioactive molecules with the potential to be developed into new drug leads. New resources are being discovered and processing techniques developed. In recent years, new interdisciplinary fields of science have emerged that allow us to engineer biological material for better industrial application with unprecedented precision.

BIOPROSP is the international biennial scientific conference on marine biotechnology that contributes to translating basic research into applied research with industrial application. BIOPROSP_19 will be held in in Tromsø, Norway, 25–27 February 2019 on the campus of the University of Tromsø—The Arctic University of Norway. The conference is organized by Tekna—The Norwegian Society of Graduate Technical and Scientific Professionals together with several collaborators.

The conference is organized in two poster sessions and four different sessions with oral presentations:

  • Biorefinery for Marine Resources
  • Synthetic Biology
  • Marine Bioactive Molecules
  • New Resources and Trends in Marine Biotech

To maximize the impact of this conference to the marine biotechnology community, the scientific committee is organizing a Special Issue of Marine Drugs dedicated to this symposium entitled “Selected Papers from the BIOPROSP_19”. We kindly invite the attendees to contribute with manuscripts for research papers or reviews for this Special Issue of Marine Drugs.

Website: https://www.tekna.no/en/events/bioprosp_19-35869/Start/

Prof. Espen Hansen
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Marine Drugs is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Published Papers (1 paper)

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Research

15 pages, 1537 KiB  
Article
Novel Vibrio spp. Strains Producing Omega-3 Fatty Acids Isolated from Coastal Seawater
by Mónica Estupiñán, Igor Hernández, Eduardo Saitua, M. Elisabete Bilbao, Iñaki Mendibil, Jorge Ferrer and Laura Alonso-Sáez
Mar. Drugs 2020, 18(2), 99; https://doi.org/10.3390/md18020099 - 1 Feb 2020
Cited by 16 | Viewed by 3853
Abstract
Omega-3 long-chain polyunsaturated fatty acids (LC-PUFAs), such as eicosapentaenoic acid (EPA) (20:5n-3) and docosahexaenoic acid (DHA) (22:6n-3), are considered essential for human health. Microorganisms are the primary producers of omega-3 fatty acids in marine ecosystems, representing a sustainable source of these lipids, as [...] Read more.
Omega-3 long-chain polyunsaturated fatty acids (LC-PUFAs), such as eicosapentaenoic acid (EPA) (20:5n-3) and docosahexaenoic acid (DHA) (22:6n-3), are considered essential for human health. Microorganisms are the primary producers of omega-3 fatty acids in marine ecosystems, representing a sustainable source of these lipids, as an alternative to the fish industry. Some marine bacteria can produce LC-PUFAs de novo via the Polyunsaturated Fatty Acid (Pfa) synthase/ Polyketide Synthase (PKS) pathway, which does not require desaturation and elongation of saturated fatty acids. Cultivation-independent surveys have revealed that the diversity of microorganisms harboring a molecular marker of the pfa gene cluster (i.e., pfaA-KS domain) is high and their potential distribution in marine systems is widespread, from surface seawater to sediments. However, the isolation of PUFA producers from marine waters has been typically restricted to deep or cold environments. Here, we report a phenotypic and genotypic screening for the identification of omega-3 fatty acid producers in free-living bacterial strains isolated from 5, 500, and 1000 m deep coastal seawater from the Bay of Biscay (Spain). We further measured EPA production in pelagic Vibrio sp. strains collected at the three different depths. Vibrio sp. EPA-producers and non-producers were simultaneously isolated from the same water samples and shared a high percentage of identity in their 16S rRNA genes, supporting the view that the pfa gene cluster can be horizontally transferred. Within a cluster of EPA-producers, we found intraspecific variation in the levels of EPA synthesis for isolates harboring different genetic variants of the pfaA-KS domain. The maximum production of EPA was found in a Vibrio sp. strain isolated from a 1000 m depth (average 4.29% ± 1.07 of total fatty acids at 10 °C, without any optimization of culturing conditions). Full article
(This article belongs to the Special Issue Selected Papers from BIOPROSP_19)
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