Liquid Biopsy in Lung Cancer: Innovations in Precision Oncology
A special issue of Journal of Personalized Medicine (ISSN 2075-4426). This special issue belongs to the section "Methodology, Drug and Device Discovery".
Deadline for manuscript submissions: 20 November 2025 | Viewed by 184
Special Issue Editors
Interests: lung cancer, head and neck tumors; artificial intelligence; cardiovascular imaging; breast imaging; preclinical imaging
Interests: radiotherapy; radiomics; oncology; lung cancer
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Liquid biopsy allows for the detection of specific mutations in circulating tumor DNA (ctDNA), such as those in the EGFR, ALK, and KRAS genes. This information is crucial for selecting targeted therapies.
Liquid biopsy helps to assess the effectiveness of therapies over time. An increase in ctDNA levels may indicate treatment resistance or disease recurrence. Liquid biopsy can identify mutations associated with drug resistance, enabling physicians to adjust treatment plans accordingly. For patients where tissue biopsies are difficult or risky, liquid biopsy provides a less invasive solution for obtaining diagnostic information. It can aid in detecting the presence of metastases and evaluating tumor heterogeneity, offering a more comprehensive view of the disease.
Liquid biopsy plays a role in lung cancer; it can be used in early diagnosis and screening for monitoring high-risk populations, allowing for the early detection of lung tumors before obvious symptoms develop. As technology advances, it will be possible to identify more mutations and biomarkers, enhancing the personalization of treatments and therapeutic effectiveness.
Research and development may contribute to clinical studies to test new therapies, improve our understanding of tumor biology, and support innovation in cancer treatment. The increasing availability of liquid biopsy could make procedures more accessible and lower the risks associated with invasive biopsies. Therefore, you are invited to submit original articles or comprehensive reviews to this Special Issue, where we aim to open up an interesting window into the future.
Dr. Maria Paola Belfiore
Dr. Valerio Nardone
Guest Editors
Manuscript Submission Information
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Keywords
- liquid biopsy
- lung cancer
- biomarkers
- diagnosis
- personalized treatment
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