Pharmacodynamics of Antifungal Drugs, 2nd Edition

Dear Colleagues,

The successful treatment of invasive fungal infections is challenging, as they often occur in patients with severely impaired immune responses. The appropriate choice and use of antifungal agents are among the cornerstones of appropriate management. Comprehensive knowledge and understanding of the pharmacodynamics of antifungal drugs elucidate dose–response relationships and are expected to lead to optimized dosage regimens in various circumstances. In this Special Issue, therefore, we invite colleagues to submit original research or review articles in the field of antifungal drug pharmacodynamics. More specific topics that could be covered include drug actions, pharmacodynamic measures of antifungal drug action (inhibitory and fungicidal concentrations, killing rates, postantifungal effects), pharmacodynamic drug–drug interactions, pharmacokinetic/pharmacodynamic characteristics of antifungal drugs (preclinical and clinical), pharmacodynamic modeling, the development of appropriate models for in vitro or in vivo pharmacodynamic studies, the evaluation of the impact of pharmacodynamic-based dosing approaches on patient outcome, and identified knowledge gaps or advances pertaining to the pharmacodynamics of already-licensed antifungal agents, as well as the pharmacodynamic properties of antifungals in clinical development. Besides these specific topics, any other papers highlighting important developments or novel perspectives in this field are welcomed.

Dr. Charalampos T. Antachopoulos
Dr. Joseph Meletiadis
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Fungi is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

• invasive fungal infections
• antifungal agents
• pharmacodynamics
• dose–response relationship
• in vivo/in vitro models