Next Generation Gene Drive for Population Modification of Mosquitoes

A special issue of Insects (ISSN 2075-4450). This special issue belongs to the section "Insect Molecular Biology and Genomics".

Deadline for manuscript submissions: closed (31 January 2024) | Viewed by 786

Special Issue Editors

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Guest Editor
Florida Medical Entomology Laboratory, University of Florida, Vero Beach, FL, USA
Interests: ecological interactions; arbovirus infection in peri-domestic and invasive mosquitoes
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Department of Biology and Biotechnology, University of Pavia, Pavia, Italy
Interests: insect-virus interactions; evolutionary biology; multitrophic interactions; applied entomology

Special Issue Information

Dear Colleagues,

More than 80% of the global population lives in areas at risk of major vector-borne diseases that account for about 17% of all infectious diseases. Mosquitos are among the most important vectors as they transmit most of the emerging and re-emerging viral infections in addition to other diseases, such as malaria. Currently, the most efficient measure to fight arboviral diseases is to limit pathogen transmission. Failure of traditional vector control methods such as insecticides due to the emergence and spread of resistance has triggered the development of alternative entomological interventions such as genetic-based strategies to alter mosquito vector competence, thus making mosquitoes incapable of carrying pathogens. This Special Issue aims to focus on the advances achieved in gene drive-based strategies to control mosquito populations. Gene-drive-based technologies can spread, modify, or suppress genetic traits to control mosquito populations or limit the transmission of mosquito-borne diseases without eradicating natural populations, which can result in a more ecosystem-friendly control. Research papers that describe gene-drive-related aspects in mosquitoes such as specific gene modulation and effect of gene drive techniques on mosquito–pathogen interactions will be considered; in addition, original reviews that review the state of the art in this field are welcome.

Dr. Barry W. Alto
Dr. Laila Gasmi
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Insects is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.


  • next-generation gene drive
  • transgenesis
  • mosquito–pathogen interaction
  • mosquito control
  • population modulation
  • population replacement

Published Papers

There is no accepted submissions to this special issue at this moment.
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