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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Drug Discovery and Development for Renal Disease Treatment
edited by
submission deadline 20 Jan 2026 | Viewed by 275 | Submission Open
Keywords: kidney disease; medicinal chemistry; drug discovery; computer-assisted drug design; drug targets; in vitro assays; epigenetic targets; multi-targeting compounds; biophysical methods; target engagement studies
(This special issue belongs to the Section Molecular Pharmacology)
Molecular Mechanisms of Animal Reproduction and Development
edited by
submission deadline 20 Jan 2026 | Viewed by 227 | Submission Open
Keywords: spermatogenesis; oogenesis; fertilization; embryogenesis; cell division; cell differentiation; stem cell; abnormal development; obesity; cancer
(This special issue belongs to the Section Molecular Biology)
New Advance in Polymers: Structuralization to Functionalization
edited by Wei Wu
submission deadline 25 Jan 2026 | Viewed by 22 | Submission Open
Keywords: polymer material; molecular weight; chain configuration; polymer chains; chemical groups
(This special issue belongs to the Section Materials Science)
Antimicrobial Materials: Molecular Developments and Applications
edited by Florina Iliescu
submission deadline 27 Jan 2026 | Viewed by 30 | Submission Open
Keywords: antimicrobial; polymers; nanotechnology; nanocomposites; molecular; green systems; POC; prophylaxis
(This special issue belongs to the Section Materials Science)
Immunotherapy Versus Immune Modulation of Leukemia
edited by Helga Maria Schmetzer
submission deadline 20 Feb 2026 | 2 articles | Viewed by 4583 | Submission Open
Keywords: leukemia; immunotherapy; immune modulation; antileukemic; drug resistance
(This special issue belongs to the Section Molecular Oncology)
Drug-Induced Modulation and Immunotherapy of Leukemia
edited by Helga Maria Schmetzer
submission deadline 20 Feb 2026 | 2 articles | Viewed by 3469 | Submission Open
Keywords: leukemia; dendritic cells; immunotherapy; immune modulation
(This special issue belongs to the Section Molecular Immunology)
Drug Discovery Based on Natural Products
edited by Woo-kyung Kim
submission deadline 28 Feb 2026 | 4 articles | Viewed by 5030 | Submission Open
Keywords: drug discovery; bioactive compounds; pharmacological activities and mechanisms; omics technologies
(This special issue belongs to the Section Molecular Pharmacology)
Hormones: Evolutionary and Functional Role
edited by
submission deadline 20 Mar 2026 | 1 articles | Viewed by 862 | Submission Open
Keywords: hormone action; brain organization; sexual behavior; endocrine tissue; receptor neuroexpression; endocrine control; endocrine disruption; climate change and reproduction; hormones and evolution
(This special issue belongs to the Section Molecular Endocrinology and Metabolism)
New Therapies and Strategies in the Treatment of Neurodegenerative Diseases submission deadline 20 Mar 2026 | 1 articles | Viewed by 679 | Submission Open
Keywords: neurodegenerative diseases; Alzheimer’ s disease; Parkinson’ s disease; Huntington’ s disease; aging; memory; dementia; motor dysfunction
(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)
Advances in Enzyme Inhibitors: Mechanisms, Applications, and Future Perspectives submission deadline 30 Mar 2026 | 4 articles | Viewed by 3658 | Submission Open
Keywords: enzyme inhibitors; drug design; drug discovery; drug therapy; resistance mechanisms; cancer; drug delivery systems; biocatalysts; enzymes in industrial applications
(This special issue belongs to the Section Biochemistry)
Research Progress of Orthopedic Materials
edited by Robert Karpiński
submission deadline 20 Apr 2026 | Viewed by 224 | Submission Open
Keywords: biocompatibility; biomaterials; orthopedic implants; hydroxyapatite; biodegradable polymers; tissue engineering; bioactive surfaces; bone cements; bone regeneration; antibacterial coatings
(This special issue belongs to the Section Materials Science)
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