Molecular Basic Research of Autoimmune Diseases
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Pathology, Diagnostics, and Therapeutics".
Deadline for manuscript submissions: 25 July 2025 | Viewed by 120
Special Issue Editor
2. Technology Commercialization Center, Office of Business Development, Taipei Medical University, Taipei 11031, Taiwan
Interests: mitochondrial disease; metabolic syndrome; metabolic reprogramming; mitochondrial biogenesis; glycolysis; oxidative stress; redox signalings; AMPK; PGC-1α; FOXO3a
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Autoimmune diseases are complex and multifaceted disorders that arise when the immune system mistakenly targets the body’s own tissues. While significant progress has been made in understanding the pathogenesis of these diseases, there remains a substantial need for further research into the mechanisms underlying autoimmune responses and the development of novel therapeutic strategies. This Special Issue aims to provide a comprehensive platform for the dissemination of recent advancements in the basic research of autoimmune diseases. The focus will be on uncovering novel molecular and cellular mechanisms, exploring the genetic and environmental factors contributing to autoimmunity, and developing innovative therapeutic approaches. Topics of interest include, but are not limited to, the following:
- Immunogenetics of Autoimmunity: Insights into genetic predispositions and epigenetic modifications contributing to autoimmune disease susceptibility.
- Immune Cell Dysregulation: Studies focusing on the roles of T cells, B cells, and other immune components in the initiation and progression of autoimmune diseases.
- Cytokines and Chemokines: Investigation into the signaling molecules that mediate inflammation and tissue damage in autoimmune diseases.
- Novel Biomarkers: Identification and validation of new biomarkers for early detection, diagnosis, and monitoring of autoimmune diseases.
- Therapeutic Targets: Exploration of new molecular targets for therapeutic intervention, including biologics, small molecules, and gene therapy.
- Environmental Triggers: The role of infections, toxins, and dietary factors in triggering autoimmune responses.
- Animal Models of Autoimmunity: The development and refinement of animal models for studying the etiology and treatment of autoimmune diseases.
- Autoimmune Disease Comorbidities: Understanding the interplay between autoimmune diseases and other health conditions, such as cardiovascular diseases, diabetes, and neurodegenerative disorders.
Dr. Shibei Wu
Guest Editor
Manuscript Submission Information
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Keywords
- autoimmune diseases
- immunogenetics
- T cells
- B cells
- cytokines
- therapeutic targets
- biomarkers
- environmental triggers
- inflammation
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